Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4146830 | 0.97 | CYP2A6 (0.55) | CYP2A6ALDH1A1LMNAKDM4ETP53 | |
| SCHEMBL2679430 | 0.97 | CYP2A6 (0.55) | CYP2A6ALDH1A1LMNAKDM4ETP53 | |
| Dimethylamine SCHEMBL6609422 | 0.90 | CYP2A6 (0.48) | CYP2A6ALDH1A1LMNAKDM4ETP53 | |
| SCHEMBL27544851 | 0.86 | CYP3A4 (0.62) | ALDH1A1LMNAKDM4ETP53CYP3A4 | |
| SCHEMBL9461723 | 0.83 | CYP3A4 (0.65) | ALDH1A1LMNAKDM4ETP53CYP3A4 | |
| SCHEMBL333123 | 0.83 | CYP3A4 (0.65) | ALDH1A1LMNAKDM4ETP53CYP3A4 | |
| SCHEMBL7527708 | 0.83 | CYP3A4 (0.65) | ALDH1A1LMNAKDM4ETP53CYP3A4 | |
| SCHEMBL9004502 | 0.80 | CYP2A6 (0.58) | CYP2A6ALDH1A1KDM4ETYRCYP2A13 | |
| SCHEMBL4195180 | 0.80 | CYP2A6 (0.58) | CYP2A6ALDH1A1KDM4ETYRCYP2A13 | |
| SCHEMBL4195177 | 0.80 | CYP2A6 (0.58) | CYP2A6ALDH1A1KDM4ETYRCYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288232-B2 | REACTION OF ACETYLNAPHTHALIC ANHYDRIDE AND ALDEHYDE IN THE PRESENCE OF AQUEOUS BASE AND BOILING IN THE PRESENCE OF ANILINE COMPOUND | EMAGIN CORPORATION | 2001-09-11 | — | — | US | disclosed |
| US-20010012905-A1 | Synthesis of pyrazolinylnaphthalic acid derivatives | EMAGIN CORPORATION | 2001-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010012905-A1 | Synthesis of pyrazolinylnaphthalic acid derivatives | AHR, NAT1, ARSA | CYP2A6 327/4885ALDH1A1 134/4885LMNA 1182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.