Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 4/20 | 0.34 |
| ▸ | ITGAV | P06756 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847593 | 0.86 | ITGB3 (0.44) | ITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7372624 | 0.84 | F2 (0.32) | ITGB3ITGA2BF2 | |
| SCHEMBL9092432 | 0.77 | ITGAV (0.50) | ITGB3ITGA2BITGAV | |
| SCHEMBL7449964 | 0.74 | ITGB3 (0.68) | ITGB3ITGA2BITGAV | |
| SCHEMBL7447180 | 0.74 | ITGB3 (0.68) | ITGB3ITGA2BITGAV | |
| SCHEMBL7442644 | 0.74 | ITGB3 (0.68) | ITGB3ITGA2BITGAV | |
| Hydrochloric Acid SCHEMBL7450135 | 0.74 | ITGB3 (0.68) | ITGB3ITGA2BITGAV | |
| SCHEMBL29373935 | 0.74 | ITGB3 (0.71) | ITGB3ITGA2B | |
| SCHEMBL9094839 | 0.73 | ITGAV (0.49) | ITGB3ITGA2BITGAV | |
| SCHEMBL7375637 | 0.73 | ITGB3 (0.45) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-B1 | ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | DU PONT PHARM CO (US) | 2001-01-17 | — | — | EP | disclosed |