SCHEMBL7848946

SCHEMBL7848946

CC(C)CCCCCC(=O)OC(C)COC(C)COC(=O)CCCCC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.42
ALDH1A1 P00352 1/20 0.42
KDM4C Q9H3R0 2/20 0.40
KDM4A O75164 1/20 0.40
PHF8 Q9UPP1 1/20 0.40
KDM2A Q9Y2K7 1/20 0.40
MAPT P10636 1/20 0.40
PRKCA P17252 1/20 0.40
PRKCE Q02156 1/20 0.40
PRKCQ Q04759 1/20 0.40
PRKCD Q05655 1/20 0.40
TLR2 O60603 3/20 0.37
EPHX2 P34913 1/20 0.37
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
ATM Q13315 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
LPAR1 Q92633 2/20 0.36
LPAR3 Q9UBY5 2/20 0.36
ENPP2 Q13822 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7850525 1.00 LMNA (0.42) LMNAALDH1A1KDM4CKDM4APHF8
SCHEMBL6062094 0.94 LMNA (0.46) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL6061623 0.94 LMNA (0.46) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL6062290 0.94 LMNA (0.46) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL536373 0.92 LMNA (0.45) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL536453 0.92 LMNA (0.45) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL480236 0.89 LMNA (0.51) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL933219 0.89 LMNA (0.51) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL1046746 0.87 LMNA (0.53) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL2248875 0.87 LMNA (0.49) LMNAALDH1A1MAPTPRKCAPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6197731-B1 PRODUCE LOWER AMOUNTS OF OBSERVABLE SMOKE IN EXHAUST EMITTED AS RESULT OF COMBUSTION IN TWO-CYCLE GASOLINE ENGINE, REQUIRE NO MISCIBILITY-ENHANCING SOLVENTS; BIODEGRADABLE HENKEL CORPORATION 2001-03-06 US disclosed
EP-0946683-A4 LUBRICANTS FOR DIESEL FUEL HENKEL CORP (US) 2001-01-03 EP disclosed
US-6080212-A DIESEL FUEL ADDITIVE COMPRISING MIXTURE OF FATTY ESTERS AND OLIGOMERIC ALIPHATIC ESTERS; SMOKELESS EXHAUST HENKEL CORPORATION (US) 2000-06-27 US disclosed
EP-0846152-A4 SMOKELESS TWO-CYCLE ENGINE LUBRICANTS HENKEL CORP (US) 2000-05-03 EP disclosed
EP-0946683-A1 LUBRICANTS FOR DIESEL FUEL HENKEL CORPORATION (US) 1999-10-06 EP disclosed
US-5925602-A LINEAR OLIGOESTER; FREE OF MISCIBILITY ENHANCERS, BIODEGRADABLE HENKEL CORPORATION (US) 1999-07-20 US disclosed
US-5912214-A POLYESTERS AND COMPLEXES HENKEL CORPORATION (US) 1999-06-15 US disclosed
EP-0846152-A2 SMOKELESS TWO-CYCLE ENGINE LUBRICANTS HENKEL CORPORATION (US) 1998-06-10 EP disclosed
WO-1998021293-A1 LUBRICANTS FOR DIESEL FUEL HENKEL CORPORATION (US) 1998-05-22 WO disclosed
WO-1997008277-A2 SMOKELESS TWO-CYCLE ENGINE LUBRICANTS HENKEL CORPORATION (US) 1997-03-06 WO disclosed