Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 7/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848981 | 0.90 | TOP2A (0.33) | TOP2ATOP2BMEN1KMT2AALDH1A1 | |
| SCHEMBL7851419 | 0.90 | ALDH1A1 (0.41) | TOP2ATOP2BMEN1KMT2AALDH1A1 | |
| SCHEMBL7853917 | 0.88 | TOP2A (0.42) | TOP2ATOP2BMEN1KMT2AALDH1A1 | |
| SCHEMBL9136070 | 0.85 | ALDH1A1 (0.51) | TOP2ATOP2BMEN1KMT2AALDH1A1 | |
| SCHEMBL7851236 | 0.82 | KDM4E (0.40) | TOP2ATOP2BMEN1KMT2AALDH1A1 | |
| SCHEMBL7853014 | 0.82 | KDM4E (0.50) | TOP2ATOP2BMEN1KMT2AALDH1A1 | |
| SCHEMBL9134891 | 0.82 | DPP4 (0.57) | TOP2ATOP2BKMT2AALDH1A1KDM4E | |
| SCHEMBL8697881 | 0.81 | CYP3A4 (0.35) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL7841699 | 0.81 | CYP3A4 (0.35) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9136774 | 0.81 | MEN1 (0.63) | TOP2ATOP2BMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726270-B1 | Derivatives of 1,6-naphthyridone carboxylic acids | BAYER AG (DE) | 2001-05-23 | — | — | EP | disclosed |
| US-5811433-A | ANTIMICROBIALS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-22 | — | — | US | disclosed |
| EP-0726270-A1 | Derivatives of 1,6-naphthyridine carboxylic acids | BAYER AG (DE) | 1996-08-14 | — | — | EP | disclosed |