SCHEMBL7849005

SCHEMBL7849005

O=[N+]([O-])c1cccnc1-c1ccc2[nH]ccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.46
NPC1 O15118 1/20 0.44
PDE4D Q08499 3/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
GRM1 Q13255 1/20 0.41
TRPV1 Q8NER1 1/20 0.41
NISCH Q9Y2I1 1/20 0.41
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
BRAF P15056 1/20 0.40
CTNNB1 P35222 1/20 0.40
WNT3A P56704 1/20 0.40
CYP17A1 P05093 1/20 0.40
CYP11B1 P15538 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15563587 0.90 ADORA2A (0.42) PDE10APDE4DALDH1A1MAPTL3MBTL1
SCHEMBL1736475 0.79 PDE10A (0.51) PDE10ANPC1PDE4DALDH1A1MAPT
SCHEMBL31069690 0.78 NPC1 (0.53) NPC1ALDH1A1MAPTCA12CA1
SCHEMBL7020065 0.78 NPC1 (0.53) NPC1ALDH1A1MAPTCA12CA1
SCHEMBL10094661 0.76 GRM1 (0.51) NPC1GRM1TRPV1NISCHBRAF
SCHEMBL8877814 0.76 MAPT (0.54) PDE10ANPC1ALDH1A1MAPTL3MBTL1
SCHEMBL18828552 0.75 NPC1 (0.59) NPC1CA12CA1CA2CA9
SCHEMBL15617224 0.74 PIM1 (0.46) NPC1ALDH1A1MAPTL3MBTL1KMT2A
SCHEMBL8523957 0.74 PI4K2A (0.51) NPC1CA12CA1CA2CA9
SCHEMBL15563066 0.74 PDE10A (0.42) PDE10APDE4DALDH1A1MAPTCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9761813-B2 Organic light-emitting compound and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2017-09-12 US disclosed
US-9761813-B2 Organic light-emitting compound and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2017-09-12 US disclosed
US-9761813-B2 Organic light-emitting compound and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2017-09-12 US disclosed
US-20150214490-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2015-07-30 US disclosed
US-20150214490-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2015-07-30 US disclosed
US-20150214490-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2015-07-30 US disclosed
WO-2014025114-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2014-02-13 WO disclosed
EP-0666858-B1 5-ARYLINDOLE DERIVATIVES AND THEIR USE AS SEROTONIN (5-HT 1) AGONISTS PFIZER (US) 2001-06-13 EP disclosed
EP-1094064-A1 5-arylindolederivatives and their use as serotonin(5-ht1)agonists PFIZER INC. (US) 2001-04-25 EP disclosed
US-5886008-A 5-arylindole derivatives PFIZER INC. (US) 1999-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150214490-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDO1, IDO2, KYNU PDE10A 2996/4885NPC1 2069/4885PDE4D 3776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.