Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 16/20 | 0.81 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 2/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850931 | 0.91 | DHPS (0.69) | DHPSADORA1DHFR | |
| SCHEMBL31037808 | 0.90 | DHPS (0.81) | DHPSEDNRAEDNRB | |
| SCHEMBL7849034 | 0.89 | DHPS (0.64) | DHPSEDNRAEDNRB | |
| SCHEMBL31037810 | 0.89 | DHPS (0.79) | DHPS | |
| SCHEMBL31037833 | 0.89 | DHPS (0.79) | DHPSEDNRAEDNRB | |
| SCHEMBL31037829 | 0.89 | DHPS (0.86) | DHPSEDNRAEDNRB | |
| SCHEMBL31037827 | 0.85 | DHPS (0.86) | DHPSEDNRAEDNRB | |
| SCHEMBL31037818 | 0.85 | DHPS (0.86) | DHPSEDNRAEDNRB | |
| SCHEMBL31037835 | 0.84 | DHPS (0.84) | DHPSEDNRA | |
| SCHEMBL31037831 | 0.83 | DHPS (0.80) | DHPSADORA1EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713875-B1 | Sulfonamides | HOFFMANN LA ROCHE (CH) | 2001-03-21 | — | — | EP | claimed |
| WO-2001049289-A1 | PHARMACEUTICAL AND VETERINARY USES OF ENDOTHELIN ANTAGONISTS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2001-07-12 | — | — | WO | disclosed |