Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.38 |
| ▸ | PTGIR | P43119 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6076259 | 0.64 | MTNR1A (0.44) | MTNR1AMTNR1BPTGIR | |
| SCHEMBL97001 | 0.61 | KMT2A (0.68) | POLB | |
| SCHEMBL3323001 | 0.61 | KMT2A (0.61) | POLB | |
| Acetic Acid SCHEMBL10568555 | 0.60 | KMT2A (0.66) | POLB | |
| Bromide SCHEMBL30703423 | 0.60 | KMT2A (0.66) | POLB | |
| Hydrochloric Acid SCHEMBL27905582 | 0.60 | KMT2A (0.66) | POLB | |
| SCHEMBL5801663 | 0.59 | KMT2A (0.65) | NPC1POLB | |
| N-Benzylmethylamine SCHEMBL2561295 | 0.59 | MAPT (0.63) | POLB | |
| SCHEMBL7202107 | 0.59 | MTNR1A (0.72) | MTNR1AMTNR1B | |
| SCHEMBL6077132 | 0.59 | MTNR1A (0.52) | MTNR1AMTNR1BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077927-A1 | NOVEL SUBSTITUTED CYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058495-A1 | NOVEL SUBSTITUTED CYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1999-11-18 | — | — | WO | disclosed |