Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029267 | 0.77 | KMT2A (0.33) | KMT2AMEN1POLBNOD1 | |
| SCHEMBL6316048 | 0.75 | KDM4E (0.46) | KMT2AKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL6432360 | 0.73 | KMT2A (0.32) | KMT2APOLBNOD1 | |
| SCHEMBL7693899 | 0.73 | PTPN1 (0.53) | KMT2AKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL6399832 | 0.72 | PTPN1 (0.39) | KMT2AKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL7562771 | 0.72 | PTPN1 (0.35) | KMT2APOLBNOD1 | |
| SCHEMBL7855098 | 0.71 | PTPN2 (0.58) | KMT2AKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL7251719 | 0.71 | — | — | |
| SCHEMBL7854135 | 0.70 | PTPN1 (0.58) | KMT2APOLBNOD1 | |
| SCHEMBL7536578 | 0.70 | PTPN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080068-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES | Novo Nordisk A/S (DK) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999046237-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES | NOVO NORDISK A/S (DK) | 1999-09-16 | — | — | WO | disclosed |