SCHEMBL784982

SCHEMBL784982

CC(=O)NC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL27486679 0.93 CRBN (0.45)
Phosphoric Acid SCHEMBL3626803 0.87 CRBN (0.41)
Diacetamide SCHEMBL28386543 0.80 FFAR3 (0.58)
Diacetamide SCHEMBL29069322 0.80 FFAR3 (0.58)
Acetic Acid SCHEMBL8393359 0.80 FFAR3 (0.58)
Diacetamide SCHEMBL97089 0.79
Diacetamide SCHEMBL635653 0.77 FFAR3 (0.54)
Diacetamide SCHEMBL29227698 0.77 FFAR3 (0.54)
Diacetamide SCHEMBL29227696 0.77 FFAR3 (0.54)
Diacetamide SCHEMBL27620016 0.77 CRBN (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112384509-B Furin inhibitors 葛兰素史密斯克莱知识产权发展有限公司 2024-04-30 CN claimed
EP-3790871-B1 FURIN INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2024-01-24 EP claimed
CN-114929220-A Small molecule furin inhibitors for the treatment of infectious diseases BP资产V股份有限公司 2022-08-19 CN claimed
CN-112384509-A Furin inhibitors 葛兰素史密斯克莱知识产权发展有限公司 2021-02-19 CN claimed
CN-1527831-A Antagonists of MCP-q function and method of use thereof ̩ 2004-09-08 CN claimed
EP-0874809-B1 CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS SMITHKLINE BEECHAM PLC (GB) 2003-08-27 EP claimed
EP-1175209-A2 USE OF ANTIEPILEPTICS FOR TREATING RESPIRATORY DISORDERS, IN PARTICULAR ASTHMATIC DISORDERS Lomia, Merab (GE) 2002-01-30 EP claimed
US-6239175-B1 Carbamoyloxy derivatives of mutiline and their use as antibacterials SMITHKLINE BEECHAM P.L.C. (GB) 2001-05-29 US claimed
WO-2000066096-A2 USE OF ANTIEPILEPTICS FOR TREATING RESPIRATORY DISORDERS, IN PARTICULAR ASTHMATIC DISORDERS LOMIA MERAB (GE) 2000-11-09 WO claimed
CN-1239473-A Method of preparing amino carboxylic acids MONSANTO CO (US) 1999-12-22 CN claimed
US-5254679-A Containing a quaternized nitrogen IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-10-19 US claimed
US-5212069-A Forming dipeptides from amides and glycine, cysteine or methionine DEGUSSA AKTIENGESELLSCHAFT (DE) 1993-05-18 US claimed
US-5134073-A Culture product of zoogloea ramigera DEGUSSA AKTIENGESELLSCHAFT (DE) 1992-07-28 US claimed
US-5049558-A Quaternized nitrogen-heterocycle substituted IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-09-17 US claimed
EP-0164944-B1 CEPHALOSPORIN DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-07-11 EP claimed
US-4909916-A Method of working up the solution from the enzymatic resolution of a racemate of an N-acetyl-DL-amino-carboxylic acid DEGUSSA AKTIENGESELLSCHAFT (DE) 1990-03-20 US claimed
EP-0232486-B1 PROCESS FOR REPROCESSING THE SOLUTION WHICH IS LEFT AFTER THE REMOVAL OF THE ENZYMES UPON THE ENZYMATIC RACEMATIC SPLITTING OF AN N-ACETYL-DL-AMINO ACID IN THE PRESENCE OF AN L-AMINO ACID ACYLASE Degussa Aktiengesellschaft (DE) 1989-09-06 EP claimed
EP-0164944-A1 Cephalosporin derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-12-18 EP claimed
US-4410522-A BACTERICIDES TOYAMA CHEMICAL CO., LTD. (JP) 1983-10-18 US claimed
JP-11180801-A None JP disclosed
EP-3450953-B1 COMPOSITION FOR PREPARING BIOLOGICAL MATERIAL HAVING EXCELLENT LIGHT TRANSMISSIVITY AND USE OF COMPOSITION RIKEN (JP) 2025-11-19 EP disclosed
US-20250179066-A1 ZWITTERIONIC ANTIBACTERIAL COMPOUNDS HOFFMANN-LA ROCHE INC. (US) 2025-06-05 US disclosed
US-12292363-B2 Method for preparing biological material having excellent light-transmitting property RIKEN (JP) 2025-05-06 US disclosed
CN-119876199-A Application of northeast wood frog lysozyme gene, mature polypeptide region gene, recombinant protein and recombinant lysozyme gene engineering bacteria 哈尔滨师范大学 2025-04-25 CN disclosed
CN-119730847-A NRF2 protein degradation agent 盖尼米德肿瘤学股份有限公司 2025-03-28 CN disclosed
US-20240417387-A1 SULFONYLPIPERAZINYL COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS HOFFMANN-LA ROCHE INC. (US) 2024-12-19 US disclosed
CN-118754943-A Fermented milk-derived polypeptide with prebiotic characteristics and preparation method thereof 宁波大学 2024-10-11 CN disclosed
CN-118584751-A POSS-based positive photoresist composition for organic insulating film 烟台希尔德材料科技有限公司 2024-09-03 CN disclosed
CN-114350694-B L-ornithine producing strain and construction method thereof 新泰市佳禾生物科技有限公司 2024-05-24 CN disclosed
CN-112384509-B Furin inhibitors 葛兰素史密斯克莱知识产权发展有限公司 2024-04-30 CN disclosed
WO-2023215378-A1 METHODS OF TREATING FIBROSIS ATHIRA PHARMA, INC. (US) 2023-11-09 WO disclosed
CN-116855484-A Phage lyase Lysrb9 and encoding gene thereof and application thereof in removal of SRB biofilm 陕西生化产业技术创新平台有限公司 2023-10-10 CN disclosed
CN-116536412-A Biomarker PGLYRP2 and application of kit thereof 山东中医药大学附属医院 2023-08-04 CN disclosed
WO-2023107597-A2 BICYCLIC HETEROAROMATIC AMIDE COMPOUNDS AND USES THEREOF Kineta, Inc. (US) 2023-06-15 WO disclosed
US-11656159-B2 Composition for preparing biological material having excellent light transmissivity and use of composition RIKEN (JP) 2023-05-23 US disclosed
CN-115943992-A Preparation method and application of perilla alcohol extract composite edible emulsion 南京工业大学 2023-04-11 CN disclosed
US-20220381657-A1 METHOD FOR PREPARING BIOLOGICAL MATERIAL HAVING EXCELLENT LIGHT-TRANSMITTING PROPERTY RIKEN (JP) 2022-12-01 US disclosed
CN-114751920-A Antitumor compounds 法马马有限公司 2022-07-15 CN disclosed
WO-2022127779-A1 SUBSTITUTED PYRIDAZINONE COMPOUND AND USE THEREOF 山东第一医科大学(山东省医学科学院) 2022-06-23 WO disclosed
CN-114350694-A L-ornithine producing strain and construction method thereof 新泰市佳禾生物科技有限公司 2022-04-15 CN disclosed
CN-113874016-A Compound and use thereof 福宏治疗公司 2021-12-31 CN disclosed
CN-112384509-A Furin inhibitors 葛兰素史密斯克莱知识产权发展有限公司 2021-02-19 CN disclosed
CN-112236172-A Methods and compounds for treating disorders 福宏治疗公司 2021-01-15 CN disclosed
EP-3724192-A1 TRIAZOLOBENZAZEPINES AS VASOPRESSIN V1A RECEPTOR ANTAGONISTS Richter Gedeon Nyrt. (HU) 2020-10-21 EP disclosed
WO-2019116324-A1 TRIAZOLOBENZAZEPINES AS VASOPRESSIN V1A RECEPTOR ANTAGONISTS RICHTER GEDEON NYRT. (HU) 2019-06-20 WO disclosed
US-20190086302-A1 COMPOSITION FOR PREPARING BIOLOGICAL MATERIAL HAVING EXCELLENT LIGHT TRANSMISSIVITY AND USE OF COMPOSITION RIKEN (JP) 2019-03-21 US disclosed
US-10227330-B2 Diaminopyrimidine derivatives and processes for the preparation thereof YUHAN CORPORATION (KR) 2019-03-12 US disclosed
US-20180265547-A1 Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2018-09-20 US disclosed
US-20180111918-A1 DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2018-04-26 US disclosed
US-9890138-B2 Diaminopyrimidine derivatives and processes for the preparation thereof YUHAN CORPORATION (KR) 2018-02-13 US disclosed
US-9811014-B2 Yellow toner and production method therefor CANON KABUSHIKI KAISHA (JP) 2017-11-07 US disclosed
EP-3196236-A1 VERTICAL ALIGNMENT FILM COMPRISING (CO)POLYMER OF CYCLIC OLEFIN COMPOUND LG Chem, Ltd. (KR) 2017-07-26 EP disclosed
US-9701146-B2 Ink set and thermal transfer recording sheet CANON KABUSHIKI KAISHA (JP) 2017-07-11 US disclosed
US-9676676-B2 Selective olefin metathesis with cyclometalated ruthenium complexes CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2017-06-13 US disclosed
EP-2875034-B1 METHOD FOR THE SYNTHESIS OF N-(PHOSPHONOMETHYL)GLYCINE STRAITMARK HOLDING AG (CH) 2017-05-03 EP disclosed
CN-104812763-B For the method synthesizing N-((phosphonomethyl)) glycine 斯特雷特马克控股股份公司 2016-11-23 CN disclosed
US-20160303882-A1 INK SET AND THERMAL TRANSFER RECORDING SHEET CANON KABUSHIKI KAISHA (JP) 2016-10-20 US disclosed
US-20160185684-A1 SELECTIVE OLEFIN METATHESIS WITH CYCLOMETALATED RUTHENIUM COMPLEXES CALIFORNIA INSTITUTE OF TECHNOLOGY 2016-06-30 US disclosed
US-20160185821-A1 Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES CALIFORNIA INSTITUTE OF TECHNOLOGY 2016-06-30 US disclosed
WO-2016014954-A1 TANDEM Z-SELECTIVE METATHESIS / DIHYDROXYLATION CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2016-01-28 WO disclosed
US-20150378273-A1 YELLOW TONER AND PRODUCTION METHOD THEREFOR CANON KABUSHIKI KAISHA (JP) 2015-12-31 US disclosed
US-9198907-B2 Combinations of a HCV inhibitor such as bicyclic pyrrole derivatives and a therapeutic agent PTC THERAPEUTICS, INC. (US) 2015-12-01 US disclosed
US-9150599-B2 Method for the synthesis of N-(phosphonomethyl)glycine STRAITMARK HOLDING AG (CH) 2015-10-06 US disclosed
US-20150274700-A2 DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2015-10-01 US disclosed
EP-2049541-B1 N-[5-({2-[(CYCLOPROPYLCARBONYL)AMINO]IMIDAZO[1,2-B]PYRIDAZIN-6-YL}OXY)-2-METHYLPHENYL]-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXAMIDE AS VEGFR INHIBITOR TAKEDA PHARMACEUTICAL (JP) 2015-09-23 EP disclosed
CN-104812763-A Method for synthesis of N-(phosphonomethyl)glycine STRAITMARK HOLDING AG 2015-07-29 CN disclosed
US-20150175635-A1 METHOD FOR THE SYNTHESIS OF N-(PHOSPHONOMETHYL)GLYCINE STRAITMARK HOLDING AG (CH) 2015-06-25 US disclosed
EP-2875034-A1 METHOD FOR THE SYNTHESIS OF N-(PHOSPHONOMETHYL)GLYCINE Straitmark Holding AG (CH) 2015-05-27 EP disclosed
US-8841302-B2 HCV inhibitor and therapeutic agent combinations PTC THERAPEUTICS, INC. (US) 2014-09-23 US disclosed
CN-102414177-B Compounds as bradykinin B1 antagonists BOEHRINGER INGELHEIM INT 2014-07-02 CN disclosed
EP-1968598-B1 PYRIMIDINE-2,4-DIAMINES AND THEIR USES RIGEL PHARMACEUTICALS INC (US) 2014-02-19 EP disclosed
CN-103588718-A Novel triazinedione derivatives as GABAB receptor modulators ADDEX PHARMA SA 2014-02-19 CN disclosed
WO-2014012988-A1 METHOD FOR THE SYNTHESIS OF N-(PHOSPHONOMETHYL)GLYCINE STRAITMARK HOLDING AG (CH) 2014-01-23 WO disclosed
US-20130338179-A1 DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2013-12-19 US disclosed
CN-101679354-B As GABABTriazinedione derivatives as receptor modulators ADDEX PHARMA SA 2013-12-18 CN disclosed
US-20130143858-A1 COMPOUNDS AND THEIR USE AS IKACH BLOCKERS ASTRAZENECA AB (SE) 2013-06-06 US disclosed
US-20130131075-A1 NEW COMPOUNDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-05-23 US disclosed
US-8361998-B2 Compounds and their use as IKACh blockers ASTRAZENECA AB 2013-01-29 US disclosed
EP-2509961-A1 IMIDAZOLIDINEDIONE DERIVATIVES Autifony Therapeutics Limited (GB) 2012-10-17 EP disclosed
US-8273741-B2 Imidazo-pyridazinyl compounds and uses thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2012-09-25 US disclosed
WO-2012074469-A1 NEW IKACH BLOCKERS ASTRAZENECA AB (SE) 2012-06-07 WO disclosed
US-20120142659-A1 COMPOUNDS AND THEIR USE AS IKACH BLOCKERS ASTRAZENECA AB (SE) 2012-06-07 US disclosed
US-20120087893-A1 COMBINATIONS OF A HCV INHIBITOR SUCH AS BICYCLIC PYRROLE DERIVATIVES AND A THERAPEUTIC AGENT PTC THERAPEUTICS, INC. (US) 2012-04-12 US disclosed
CN-102414177-A Compounds as bradykinin b1 antagonists BOEHRINGER INGELHEIM INT 2012-04-11 CN disclosed
US-8153682-B2 Sulfonamides as TRPM8 modulators JANSSEN PHARMACEUTICA, NV (BE) 2012-04-10 US disclosed
US-20120070412-A1 HCV Inhibitor and Therapeutic Agent Combinations PTC THERAPEUTICS, INC. (US) 2012-03-22 US disclosed
US-8084615-B2 Antibacterial agents UNIVERSITY OF WASHINGTON (US) 2011-12-27 US disclosed
US-8044049-B2 Fused heterocyclic derivative and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-10-25 US disclosed
US-8034812-B2 Imidazopyridazine derivative having kinase inhibitory activity and pharmaceutical agent thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-10-11 US disclosed
EP-2351827-A1 Culture medium for cell growth and transfection Life Technologies Corporation (US) 2011-08-03 EP disclosed
WO-2011084991-A2 FLUORINATED HDAC INHIBITORS AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2011-07-14 WO disclosed
WO-2011069951-A1 IMIDAZOLIDINEDIONE DERIVATIVES GLAXO GROUP LIMITED (GB) 2011-06-16 WO disclosed
US-20110104076-A1 Compositions, Methods For Preparing Amino Acids And Nuclear Magnetic Resonance Spectroscopy GLYCONIX CORPORATION 2011-05-05 US disclosed
US-20100311757-A1 Salarins And Tulearins, Compositions And Uses Thereof RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2010-12-09 US disclosed
US-20100273788-A1 FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-10-28 US disclosed
WO-2010107739-A2 METHODS AND COMPOSITIONS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2010-09-23 WO disclosed
WO-2010107742-A2 METHODS AND COMPOSITIONS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2010-09-23 WO disclosed
US-20100240669-A1 NEW COMPOUNDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-09-23 US disclosed
US-20100168424-A1 FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-07-01 US disclosed
EP-2200995-A2 SALARINS AND TULEARINS, COMPOSITIONS AND USES THEREOF Ramot at Tel-Aviv University Ltd (IL) 2010-06-30 EP disclosed
US-7713987-B2 Pyrimidine-2,4-diamines and their uses RIGEL PHARMACEUTICALS, INC. (US) 2010-05-11 US disclosed
CN-101679354-A As GABABNovel triazinedione derivatives as receptor modulators ADDEX PHARMACEUTICALS SA 2010-03-24 CN disclosed
US-20090306374-A1 FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-12-10 US disclosed
US-20090264474-A1 SULFONAMIDES AS TRPM8 MODULATORS JANSSEN PHARMACEUTICA, N.V. (BE) 2009-10-22 US disclosed
CN-101541801-A Fused heterocyclic derivative and use thereof TAKEDA PHARMACEUTICAL (JP) 2009-09-23 CN disclosed
EP-1268443-B1 2-HYDROXY-MUTILIN CARBAMATE DERIVATIVES FOR ANTIBACTERIAL USE SMITHKLINE BEECHAM PLC (GB) 2009-07-29 EP disclosed
US-20090163496-A1 ANTIBACTERIAL AGENTS UNIVERSITY OF WASHINGTON (US) 2009-06-25 US disclosed
US-20090137595-A1 FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-05-28 US disclosed
CN-101426785-A Adenosine A3 receptor agonists NOVARTIS AG (CH) 2009-05-06 CN disclosed
EP-2049541-A2 FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF Takeda Pharmaceutical Company Limited (JP) 2009-04-22 EP disclosed
WO-2009040817-A2 SALARINS AND TULEARINS, COMPOSITIONS AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2009-04-02 WO disclosed
WO-2009039248-A2 METHODS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION AND COMPOSITIONS FOR TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION STANFORD UNIVERSITY (US) 2009-03-26 WO disclosed
WO-2009039246-A2 METHODS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION, COMPOSITIONS FOR TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION, AND SCREENING ASSAYS FOR IDENTIFYING COMPOSITIONS FOR TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION STANFORD UNIVERSITY (US) 2009-03-26 WO disclosed
US-20080275112-A1 Invention Concerning Aminoadamantane Compounds SCHREINER PETER R 2008-11-06 US disclosed
US-7446109-B2 Carbonylamino-derivatives as novel inhibitors of histone deacetylase JANSSEN PHARMACEUTICA N.V. (BE) 2008-11-04 US disclosed
US-7446109-B2 Carbonylamino-derivatives as novel inhibitors of histone deacetylase JANSSEN PHARMACEUTICA N.V. (BE) 2008-11-04 US disclosed
EP-1968598-A1 PYRIMIDINE-2,4-DIAMINES AND THEIR USES Rigel Pharmaceuticals, Inc. (US) 2008-09-17 EP disclosed
WO-2008088303-A1 PYRIMIDINE-2,4-DIAMINES AND THEIR USES RIGEL, PHARMACEUTICALS, INC. (US) 2008-07-24 WO disclosed
EP-1942888-A2 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS Cytokinetics, Inc. (US) 2008-07-16 EP disclosed
EP-1248612-B1 NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS MERCK FROSST CANADA LTD (CA) 2008-02-27 EP disclosed
WO-2008016192-A2 FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-02-07 WO disclosed
CN-101039701-A Prodrugs and codrug comprising a biocleavable disulfide linker NICHOLAS PIRAMAL INDIA LTD (IN) 2007-09-19 CN disclosed
US-20070161681-A1 ETHER DERIVATIVES USEFUL AS INHIBITORS OF PDE4 ISOZYMES PFIZER INC. (US) 2007-07-12 US disclosed
WO-2007070195-A2 COMPOSITIONS, METHODS OF PREPARING AMINO ACIDS AND NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY GLYCONIX CORPORATION (US) 2007-06-21 WO disclosed
US-20070129362-A1 Pyrimidine-2,4-diamines and their uses MIDCAP FINANCIAL TRUST 2007-06-07 US disclosed
US-20070129360-A1 N2-Chlorocarbonyl-N4-(2,2-dimethyl-3-oxo-4H-5-pyrido[1,4]oxazin-6-yl)-5-fluoro-N2-(3,4,5-trimethoxyphenyl)-2,4-pyrimidinediamine; kinase inhibitors; breast cancer; inhibiting signal transduction cascades in which Syk plays a role PHAMIDIPATI SOMASEKHAR 2007-06-07 US disclosed
WO-2007056078-A2 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS CYTOKINETICS, INC. (US) 2007-05-18 WO disclosed
CN-1315929-C Rubber composition for tread and pneumatic tyre using the same SUMITOMO RUBBER IND (JP) 2007-05-16 CN disclosed
US-20070104648-A1 Compositions, methods of preparing amino acids, and nuclear magnetic resonance spectroscopy GLYCONIX CORPORATION 2007-05-10 US disclosed
US-7183293-B2 Ether derivatives useful as inhibitors of PDE4 isozymes PFIZER INC. (US) 2007-02-27 US disclosed
CN-1832936-A Processes for the preparation of n-((((pyridinyloxy)-phenylamino)quinazolinyl)-allyl)acetamide derivatives and related compounds as well as intermediates of such processes and processes for the prepar PFIZER PROD INC (US) 2006-09-13 CN disclosed
CN-1245979-C Medicine for preventing and treating dermatitis containing chymase inhibitor as active ingredient DAIICHI ASBIAO PHARMACEUTICAL (JP) 2006-03-22 CN disclosed
CN-1245978-C Preventive and therapeutic agent for various diseases associated with eosinophilia comprising chymase inhibitor as active ingredient DAIICHI ASBIAO PHARMACEUTICAL (JP) 2006-03-22 CN disclosed
EP-1248612-A4 NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS MERCK FROSST CANADA INC (CA) 2005-09-07 EP disclosed
CN-1216872-C Quinazoline derivative and pharmaceutical use thereof SUNTORY LTD (JP) 2005-08-31 CN disclosed
CN-1643158-A Process for preparing optically active beta-aminocarboxylic acids from racemic N-acylated beta-aminocarboxylic acids DEGUSSA (DE) 2005-07-20 CN disclosed
US-20050153401-A1 Process for preparing optically active beta-aminocarboxylic acids from racemic n-acylated beta-aminocarboxylic acids DEGUSSA AG (DE) 2005-07-14 US disclosed
US-20050124652-A1 Guanidino compounds BOYCE RUSTUM (US) 2005-06-09 US disclosed
CN-1572825-A Rubber composition for tread and pneumatic tyre using the same SUMITOMO RUBBER IND (JP) 2005-02-02 CN disclosed
EP-1487990-A2 PROCESS FOR PREPARING OPTICALLY ACTIVE BETA-AMINOCARBOXYLIC ACIDS FROM RACEMIC N-ACYLATED BETA-AMINOCARBOXYLIC ACIDS Degussa AG (DE) 2004-12-22 EP disclosed
EP-1399420-A2 PYRROLIDINES AS DIPEPTIDYL PEPTIDASE INHIBITORS SmithKline Beecham Corporation (US) 2004-03-24 EP disclosed
WO-2003080854-A2 PROCESS FOR PREPARING OPTICALLY ACTIVE BETA-AMINOCARBOXYLIC ACIDS FROM RACEMIC N-ACYLATED BETA-AMINOCARBOXYLIC ACIDS DEGUSSA AG (DE) 2003-10-02 WO disclosed
EP-0874809-B1 CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS SMITHKLINE BEECHAM PLC (GB) 2003-08-27 EP disclosed
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP disclosed
EP-0733645-B1 NOVEL SYNTHETIC PEPTIDE, LUNG SURFACTANT CONTAINING THE SAME, AND REMEDY FOR RESPIRATORY DISTRESS SYNDROME MITSUBISHI PHARMA CORP (JP) 2003-03-19 EP disclosed
US-6525036-B2 Treating post-menopausal osteoporosis. MERCK & CO., INC. 2003-02-25 US disclosed
WO-2003002530-A2 PYRROLIDINES AS DIPEPTIDYL PEPTIDASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2003-01-09 WO disclosed
EP-1248612-A1 NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS MERCK FROSST CANADA INC. (CA) 2002-10-16 EP disclosed
CN-1366461-A Preventive or therapeutic drugs for dermatitises containing chymase inhibitors as active ingredient SUNTORY LTD (JP) 2002-08-28 CN disclosed
CN-1366459-A Preventive and therapeutic agent for various diseases associated with eosinophilia comprising chymase inhibitor as active ingredient SUNTORY LTD (JP) 2002-08-28 CN disclosed
CN-1366460-A Preventive or therapeutic drugs for fibrosis containing chymase inhibitors as active ingredient SUNTORY LTD (JP) 2002-08-28 CN disclosed
US-20020052378-A1 Novel compounds and compositions as protease inhibitors Celera Corporation 2002-05-02 US disclosed
CN-1335778-A Blood vessel lipid deposition inhibitor containing chymotrypsin inhibitor SUNTORY LTD (JP) 2002-02-13 CN disclosed
EP-1175209-A2 USE OF ANTIEPILEPTICS FOR TREATING RESPIRATORY DISORDERS, IN PARTICULAR ASTHMATIC DISORDERS Lomia, Merab (GE) 2002-01-30 EP disclosed
WO-2001049288-A9 NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS MERCK FROSST CANADA INC (CA) 2001-10-25 WO disclosed
CN-1319096-A Quinazoline derivative and pharmaceutical use thereof SUNTORY LTD (JP) 2001-10-24 CN disclosed
WO-2001049288-A1 NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS MERCK FROSST CANADA & CO. (CA) 2001-07-12 WO disclosed
US-6239175-B1 Carbamoyloxy derivatives of mutiline and their use as antibacterials SMITHKLINE BEECHAM P.L.C. (GB) 2001-05-29 US disclosed
WO-2000066096-A2 USE OF ANTIEPILEPTICS FOR TREATING RESPIRATORY DISORDERS, IN PARTICULAR ASTHMATIC DISORDERS LOMIA MERAB (GE) 2000-11-09 WO disclosed
US-6114163-A ACETYLATING RACEMIC MIXTURE, NEUTRALIZING SOLUTION, DEACETYLING USING STEREOSPECIFIC ACYLASE TO PRODUCE L-STEREOISOMERS, SEPARATING OUT WANTED PRODUCT, ADJUSTING SOLUTION, RACEMIZING MIXTURE, AND DEACETYLATING AGAIN DEGUSSA AKTIENGESELLSCHAFT (DE) 2000-09-05 US disclosed
US-6080887-A HEATING A MIXTURE COMPRISING THE RACEMIC MIXTURE WITH AT LEAST ONE ALKALI OR ALKALINE EARTH SALT OF N-ACETYL-D(L)-.ALPHA.-AMINO CARBOXYLIC ACID AND ACETIC ANHYDRIDE UNDER NON-AQUEOUS CONDITIONS DEGUSSA AKTIENGESELLSCHAFT (DE) 2000-06-27 US disclosed
EP-0487301-B1 Method of stabilizing enzyme conjugates DADE BEHRING MARBURG GMBH (DE) 2000-05-31 EP disclosed
US-6020368-A MICROBIOCIDES HINKS JEREMY DAVID (US) 2000-02-01 US disclosed
EP-0924263-B1 Disazo dyes, their preparation and use thereof ILFORD IMAGING CH GMBH (CH) 1999-07-28 EP disclosed
JP-H11180801-A PLANT FRESHNESS MAINTAINING AGENT AND PLANT TREATED WITH THE AGENT AFTER HARVEST DAIWA KASEI KENKYUSHO:KK 1999-07-06 JP disclosed
EP-0924263-A1 Disazo dyes, their preparation and use thereof ILFORD Imaging Switzerland GmbH (CH) 1999-06-23 EP disclosed
EP-0874809-A1 CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS SMITHKLINE BEECHAM PLC (GB) 1998-11-04 EP disclosed
US-5827825-A POLYPEPTIDE FROM THE CONDENSATION OF VARIABLE HEXA- OR HEPTAPEPTIDES WITH PEPTIDES CONTAINING TWELVE TO TWENTY UNITS OF LEUCINE AND/OR NORLEUCINE, FOR TREATMENT OF RESPIRATORY DISORDERS TOKYO TANABE COMPANY LTD. (JP) 1998-10-27 US disclosed
US-5686253-A Method of stabilizing enzyme conjugates BEHRINGWERKE AG (DE) 1997-11-11 US disclosed
WO-1997025309-A1 CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS SMITHKLINE BEECHAM PLC (GB) 1997-07-17 WO disclosed
US-5614351-A Radiation-curable mixture, and radiation-sensitive recording material produced therefrom for high-energy radiation HOECHST AKTIENGESELLSCHAFT (DE) 1997-03-25 US disclosed
EP-0733645-A1 NOVEL SYNTHETIC PEPTIDE, LUNG SURFACTANT CONTAINING THE SAME, AND REMEDY FOR RESPIRATORY DISTRESS SYNDROME TOKYO TANABE COMPANY LIMITED (JP) 1996-09-25 EP disclosed
EP-0300665-B1 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions ZENECA PHARMA SA (FR) 1995-12-20 EP disclosed
EP-0304155-B1 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions ZENECA PHARMA SA (FR) 1995-11-15 EP disclosed
US-5254679-A Containing a quaternized nitrogen IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-10-19 US disclosed
US-5212069-A Forming dipeptides from amides and glycine, cysteine or methionine DEGUSSA AKTIENGESELLSCHAFT (DE) 1993-05-18 US disclosed
US-5210202-A Chiral phosphorous compounds, a process for their manufacture and their application to the catalysis of enantioselective synthesis reactions SOCIETE CHIMIQUE DES CHARBONNAGES S.A. (FR) 1993-05-11 US disclosed
EP-0225182-B1 CEPHALOSPORIN COMPOUNDS ICI PHARMA (FR) 1993-02-10 EP disclosed
US-5134073-A Culture product of zoogloea ramigera DEGUSSA AKTIENGESELLSCHAFT (DE) 1992-07-28 US disclosed
EP-0487301-A1 Method of stabilizing enzyme conjugates BEHRINGWERKE Aktiengesellschaft (DE) 1992-05-27 EP disclosed
US-5099077-A Dihydrocarbylphosphioxy substituted groups with amine or phosphinoamines as ligands SOCIETE CHIMIQUE DES CHARBONNAGES S.A. (FR) 1992-03-24 US disclosed
US-5049558-A Quaternized nitrogen-heterocycle substituted IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-09-17 US disclosed
US-5013731-A Bactericides ICI PHARMA (FR) 1991-05-07 US disclosed
US-5013730-A Antibiotics ICI-PHARMA (FR) 1991-05-07 US disclosed
US-5008258-A Antibiotics I.C.I.-PHARMA (FR) 1991-04-16 US disclosed
EP-0164944-B1 CEPHALOSPORIN DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-07-11 EP disclosed
EP-0374415-A2 Thickening agents for aqueous surfactant compositions HÜLS AKTIENGESELLSCHAFT (DE) 1990-06-27 EP disclosed
EP-0374414-A2 Use of thickener compositions for surfactants and surfactant systems HÜLS AKTIENGESELLSCHAFT (DE) 1990-06-27 EP disclosed
US-4909916-A Method of working up the solution from the enzymatic resolution of a racemate of an N-acetyl-DL-amino-carboxylic acid DEGUSSA AKTIENGESELLSCHAFT (DE) 1990-03-20 US disclosed
US-4909916-A Method of working up the solution from the enzymatic resolution of a racemate of an N-acetyl-DL-amino-carboxylic acid DEGUSSA AKTIENGESELLSCHAFT (DE) 1990-03-20 US disclosed
US-4909916-A Method of working up the solution from the enzymatic resolution of a racemate of an N-acetyl-DL-amino-carboxylic acid DEGUSSA AKTIENGESELLSCHAFT (DE) 1990-03-20 US disclosed
US-4877908-A Chiral phosphorus compounds, a process for their manufacture and their application to the catalysis of enantioselective synthesis reactions NORSOLOR (FR) 1989-10-31 US disclosed
EP-0232486-B1 PROCESS FOR REPROCESSING THE SOLUTION WHICH IS LEFT AFTER THE REMOVAL OF THE ENZYMES UPON THE ENZYMATIC RACEMATIC SPLITTING OF AN N-ACETYL-DL-AMINO ACID IN THE PRESENCE OF AN L-AMINO ACID ACYLASE Degussa Aktiengesellschaft (DE) 1989-09-06 EP disclosed
EP-0304155-A2 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions ZENECA Pharma S.A. (FR) 1989-02-22 EP disclosed
EP-0300664-A2 Cephalosporin compounds ZENECA Pharma S.A. (FR) 1989-01-25 EP disclosed
EP-0300665-A2 Cephalosporin compounds, process for their preparation and their pharmaceutical compositions ZENECA Pharma S.A. (FR) 1989-01-25 EP disclosed
US-4699999-A REMOVAL OF COBALT CATALYSTS BY NEUTRALIZATION DYNAMIT NOBEL AG (DE) 1987-10-13 US disclosed
US-4592774-A Herbicidal alpha heterocyclic carbinol carbamates, ureas and N-alpha-substituted acetylcarbamates UNION CARBIDE CORPORATION (US) 1986-06-03 US disclosed
US-4592774-A Herbicidal alpha heterocyclic carbinol carbamates, ureas and N-alpha-substituted acetylcarbamates UNION CARBIDE CORPORATION (US) 1986-06-03 US disclosed
US-4592774-A Herbicidal alpha heterocyclic carbinol carbamates, ureas and N-alpha-substituted acetylcarbamates UNION CARBIDE CORPORATION (US) 1986-06-03 US disclosed
EP-0164944-A1 Cephalosporin derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-12-18 EP disclosed
US-4410522-A BACTERICIDES TOYAMA CHEMICAL CO., LTD. (JP) 1983-10-18 US disclosed
US-4379152-A Cephalosporins TOYAMA CHEMICAL CO., LTD. (JP) 1983-04-05 US disclosed
US-4327097-A BACTERICIDES FOR MAMMALS TOYAMA CHEMICAL CO., LTD. (JP) 1982-04-27 US disclosed
US-4234578-A ANTIBIOTICS CIBA-GEIGY CORPORATION (US) 1980-11-18 US disclosed
US-4219554-A Novel penicillins and cephalosporins and process for producing same TOYAMA CHEMICAL COMPANY, LIMITED (JP) 1980-08-26 US disclosed
US-4112090-A BACTERICIDE TOYAMA CHEMICAL CO., LTD. (JP) 1978-09-05 US disclosed
US-4110327-A BACTERICIDES TOYAMA CHEMICAL CO., LTD. (JP) 1978-08-29 US disclosed
US-4087424-A Novel penicillins and cephalosporins and process for producing the same TOYAMA CHEMICAL CO., LTD. (JA) 1978-05-02 US disclosed
US-4005088-A Process for the chemical separation of racemic modifications of α-aminocarboxylic acid derivatives, and cinchonidine salt intermediates ANDENO B.V. (NL) 1977-01-25 US disclosed
US-4005088-A Process for the chemical separation of racemic modifications of α-aminocarboxylic acid derivatives, and cinchonidine salt intermediates ANDENO B.V. (NL) 1977-01-25 US disclosed