Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.60 |
| ▸ | BCHE | P06276 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7849967 | 1.00 | CYP1B1 (0.62) | CYP1B1ABCG2MAPTLMNAL3MBTL1 | |
| SCHEMBL7849969 | 0.87 | MAPT (0.68) | CYP1B1ABCG2MAPTLMNAL3MBTL1 | |
| SCHEMBL31233508 | 0.83 | MAPT (0.73) | CYP1B1ABCG2MAPTLMNABCHE | |
| SCHEMBL17047851 | 0.83 | MAPT (0.73) | CYP1B1ABCG2MAPTLMNABCHE | |
| SCHEMBL30383301 | 0.83 | MAPT (0.73) | CYP1B1ABCG2MAPTLMNABCHE | |
| SCHEMBL25202121 | 0.83 | MAPT (0.73) | CYP1B1ABCG2MAPTLMNABCHE | |
| SCHEMBL17047852 | 0.83 | MAPT (0.73) | CYP1B1ABCG2MAPTLMNABCHE | |
| SCHEMBL7841355 | 0.82 | MAPT (0.54) | CYP1B1ABCG2MAPTLMNAL3MBTL1 | |
| SCHEMBL7913782 | 0.81 | CYP1B1 (0.71) | CYP1B1ABCG2MAPTLMNAL3MBTL1 | |
| SCHEMBL699741 | 0.81 | CYP1B1 (0.71) | CYP1B1ABCG2MAPTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288232-B2 | REACTION OF ACETYLNAPHTHALIC ANHYDRIDE AND ALDEHYDE IN THE PRESENCE OF AQUEOUS BASE AND BOILING IN THE PRESENCE OF ANILINE COMPOUND | EMAGIN CORPORATION | 2001-09-11 | — | — | US | disclosed |
| US-20010012905-A1 | Synthesis of pyrazolinylnaphthalic acid derivatives | EMAGIN CORPORATION | 2001-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010012905-A1 | Synthesis of pyrazolinylnaphthalic acid derivatives | AHR, NAT1, ARSA | CYP1B1 39/4885ABCG2 342/4885MAPT 2130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.