Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.74 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.74 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7853305 | 0.90 | AGTR1 (0.59) | AGTR1AGTR2ENPP2LMNAALDH1A1 | |
| SCHEMBL9196687 | 0.85 | AGTR1 (1.00) | AGTR1AGTR2 | |
| SCHEMBL7853694 | 0.83 | AGTR1 (0.71) | AGTR1AGTR2ENPP2LMNAALDH1A1 | |
| SCHEMBL7851373 | 0.82 | AGTR1 (0.75) | AGTR1AGTR2 | |
| SCHEMBL9137163 | 0.81 | AGTR1 (0.51) | AGTR1AGTR2ENPP2LMNAALDH1A1 | |
| SCHEMBL9137175 | 0.81 | AGTR1 (0.51) | AGTR1AGTR2ENPP2LMNAALDH1A1 | |
| SCHEMBL9235936 | 0.80 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9096716 | 0.80 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL9571356 | 0.79 | AGTR1 (0.56) | AGTR1AGTR2ENPP2 | |
| SCHEMBL9308166 | 0.79 | AGTR1 (0.54) | AGTR1AGTR2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399731-B2 | Azaindenes | ASTRAZENECA AB (SE) | 2001-07-11 | — | — | EP | disclosed |
| EP-0399731-B1 | Azaindenes | ZENECA LTD (GB) | 1993-12-08 | — | — | EP | disclosed |
| EP-0399731-A1 | Azaindenes | ZENECA LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |