Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 7/20 | 0.50 |
| ▸ | NOS3 | P29474 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835034 | 0.81 | AOC3 (0.35) | NOS2NOS3LMNAALDH1A1KDM4E | |
| SCHEMBL4989950 | 0.78 | NOS2 (0.56) | NOS2NOS3LMNAKDM4ENOS1 | |
| SCHEMBL31214543 | 0.74 | NOS2 (0.42) | NOS2NOS3LMNAALDH1A1KDM4E | |
| SCHEMBL18753742 | 0.74 | NOS2 (0.34) | NOS2NOS3LMNAALDH1A1KDM4E | |
| SCHEMBL12048608 | 0.72 | KDM4E (0.45) | NOS2NOS3LMNAALDH1A1KDM4E | |
| SCHEMBL2130737 | 0.72 | GAA (0.39) | LMNAALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL7841702 | 0.70 | SMN1; SMN2 (0.48) | LMNAALDH1A1SMN1; SMN2HASPINHPGD | |
| SCHEMBL11489975 | 0.69 | NOS2 (0.56) | NOS2NOS3LMNAKDM4ENOS1 | |
| SCHEMBL30374657 | 0.68 | — | — | |
| SCHEMBL1502884 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717743-B1 | N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-0972774-A2 | 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-pyridines | Dow AgroSciences LLC (US) | 2000-01-19 | — | — | EP | disclosed |
| US-5700940-A | FOR PRE- OR POSTEMERGENCE SPRAYING OF PLANTS OR SOILS | DOWELANCO (US) | 1997-12-23 | — | — | US | disclosed |
| US-5614469-A | N-pyridinyl[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1997-03-25 | — | — | US | disclosed |
| US-5571775-A | EFFECTIVE ON A BROAD SPECTRUM OF VEGETATION AT LOW APPLICATION RATES | DOWELANCO (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0717743-A1 | N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOWELANCO (US) | 1996-06-26 | — | — | EP | disclosed |
| WO-1996001826-A1 | N-ARYL[1,2,4]TRIAZOLO[1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOWELANCO (US) | 1996-01-25 | — | — | WO | disclosed |
| WO-1996001828-A1 | N-PYRIDINYL[1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE-2-SULFONAMIDE HERBICIDES | DOWELANCO (US) | 1996-01-25 | — | — | WO | disclosed |
| US-5461161-A | Chemical intermediate is 3-amino-2-hal pyridine | DOWELANCO (US) | 1995-10-24 | — | — | US | disclosed |