Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL975422 | 0.80 | IDO1 (0.48) | IDO1TAAR1CYP2A6ALDH1A1TDP1 | |
| SCHEMBL27586168 | 0.78 | NQO1 (0.58) | CA2ALDH1A1SMN1; SMN2TSHRTDP1 | |
| SCHEMBL190895 | 0.76 | IDO1 (0.55) | IDO1TP53CA2TAAR1ALDH1A1 | |
| SCHEMBL7850364 | 0.76 | IDO1 (0.54) | IDO1TP53CA2TAAR1CYP2A6 | |
| SCHEMBL8824002 | 0.75 | APP (0.46) | IDO1DAOCYP3A4 | |
| SCHEMBL27770079 | 0.75 | IDO1 (0.48) | IDO1TP53TAAR1ALDH1A1TDP1 | |
| SCHEMBL7308941 | 0.75 | IDO1 (0.48) | IDO1TAAR1CYP2A6ALDH1A1L3MBTL1 | |
| SCHEMBL9195186 | 0.75 | ESR1 (0.48) | IDO1CA2TAAR1ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5797808 | 0.75 | IDO1 (0.56) | IDO1TP53CA2TAAR1ALDH1A1 | |
| SCHEMBL28321938 | 0.75 | IDO1 (0.50) | IDO1ALDH1A1SMN1; SMN2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |