SCHEMBL7308941

SCHEMBL7308941

Clc1ccc(CSOSCc2ccc(Cl)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.48
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
MAPK1 P28482 1/20 0.45
NPC1 O15118 1/20 0.45
ALDH1A1 P00352 1/20 0.45
RAB9A P51151 1/20 0.45
AGXT P21549 2/20 0.44
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
CYP1A2 P05177 2/20 0.42
CYP2C19 P33261 2/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2D6 P10635 2/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
LMNA P02545 1/20 0.40
CYP2A6 P11509 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20863645 0.77 IDO1 (0.52) IDO1MEN1KMT2AMAPK1NPC1
SCHEMBL8716375 0.76 IDO1 (0.46) IDO1MEN1KMT2AMAPK1NPC1
SCHEMBL3674399 0.76 CYP1A2 (0.63) IDO1MEN1KMT2AMAPK1NPC1
SCHEMBL1082679 0.76 IDO1 (0.54) IDO1MEN1KMT2AMAPK1NPC1
SCHEMBL9195186 0.75 ESR1 (0.48) IDO1MEN1KMT2ANPC1ALDH1A1
SCHEMBL975422 0.75 IDO1 (0.48) IDO1ALDH1A1RAB9AAGXTBCHE
SCHEMBL28429181 0.75 ALDH1A1 (0.48) MEN1KMT2AMAPK1NPC1ALDH1A1
SCHEMBL27770079 0.75 IDO1 (0.48) IDO1KMT2ANPC1ALDH1A1RAB9A
SCHEMBL7850367 0.75 IDO1 (0.48) IDO1MAPK1ALDH1A1ACHECYP1A2
SCHEMBL8824002 0.75 APP (0.46) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104230804-B The preparation method of chemiluminescent substance APS-5 key intermediate YUNNAN UNIVERSITY OF NATIONALITIES (CN) 2016-05-25 CN claimed
US-11970694-B2 Rapid display method in translational synthesis of peptide PEPTIDREAM INC. (JP) 2024-04-30 US disclosed
US-20200199579-A1 Rapid Display Method in Translational Synthesis of Peptide PEPTIDREAM INC (JP) 2020-06-25 US disclosed
EP-2492344-B1 RAPID DISPLAY METHOD IN TRANSLATIONAL SYNTHESIS OF PEPTIDE PEPTIDREAM INC (JP) 2016-04-06 EP disclosed
EP-2492344-A9 RAPID DISPLAY METHOD IN TRANSLATIONAL SYNTHESIS OF PEPTIDE PeptiDream Inc. (JP) 2013-02-20 EP disclosed
EP-2492344-A1 RAPID DISPLAY METHOD IN TRANSLATIONAL SYNTHESIS OF PEPTIDE PeptiDream Inc. (JP) 2012-08-29 EP disclosed
US-20120208720-A1 RAPID DISPLAY METHOD IN TRANSLATIONAL SYNTHESIS OF PEPTIDE PEPTIDREAM INC. (JP) 2012-08-16 US disclosed
CN-1029383-C 1-Dimethylcarbamoyl-3-substituted-5-substituted-1H-1,2,4-triazoles SHELL INT RESEARCH (NL) 1995-08-02 CN disclosed
EP-0520336-A2 Aldehyde derivatives and their use as calpain inhibitors FUJIREBIO Inc. (JP) 1992-12-30 EP disclosed
CN-1037897-A 1-formyl-dimethylamino-3-replacement-5-replacement-1H-1,2, the 4-triazole ROHM & HAAS (US) 1989-12-13 CN disclosed
CN-1037340-A 1-dimethylin formyl radical-3-replacement-5-replacement-1H-1,2, the 4-triazole ROHM & HAAS (US) 1989-11-22 CN disclosed