SCHEMBL7850508

SCHEMBL7850508

O=C(CCCC1CCN(Cc2ccccc2)CC1)c1ccc2c(c1)CCN(Cc1ccccc1)CC2

nearest known ligand 0.74

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE P22303 16/20 0.74
BCHE P06276 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7226490 0.99 ACHE (0.73) ACHEBCHE
SCHEMBL7226892 0.96 ACHE (0.69) ACHE
Hydrochloric Acid SCHEMBL7236234 0.96 ACHE (0.71) ACHEBCHE
SCHEMBL7846382 0.93 ACHE (0.84) ACHEBCHE
Hydrochloric Acid SCHEMBL7234767 0.93 ACHE (0.66) ACHE
SCHEMBL7234383 0.93 ACHE (0.66) ACHE
Hydrochloric Acid SCHEMBL7227921 0.93 ACHE (0.66) ACHEBCHE
Hydrochloric Acid SCHEMBL7236442 0.93 ACHE (0.66) ACHEBCHE
Hydrochloric Acid SCHEMBL7233924 0.92 ACHE (0.65) ACHE
SCHEMBL7233798 0.92 ACHE (0.64) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1122252-A1 NITROGENOUS FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME Takeda Chemical Industries, Ltd. (JP) 2001-08-08 EP disclosed