Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850679 | 0.89 | DPP4 (0.65) | DPP4CHRM2DRD1KMT2AKDM4E | |
| SCHEMBL9066624 | 0.89 | DPP4 (0.65) | DPP4CHRM2DRD1KMT2AKDM4E | |
| SCHEMBL9066534 | 0.89 | DPP4 (0.65) | DPP4CHRM2DRD1KMT2AKDM4E | |
| SCHEMBL9838906 | 0.88 | KMT2A (0.56) | DPP4CHRM2DRD1KMT2AKDM4E | |
| SCHEMBL9645658 | 0.88 | KMT2A (0.56) | DPP4CHRM2DRD1KMT2AKDM4E | |
| SCHEMBL7853994 | 0.87 | KMT2A (0.43) | DPP4CHRM2DRD1KMT2AKDM4E | |
| SCHEMBL10745216 | 0.84 | DPP4 (0.49) | DPP4CHRM2DRD1KMT2AKDM4E | |
| SCHEMBL9691077 | 0.84 | KCNH2 (0.53) | DPP4CHRM2DRD1KMT2AKDM4E | |
| SCHEMBL9647228 | 0.83 | DPP4 (0.53) | DPP4CHRM2DRD1KMT2AKDM4E | |
| SCHEMBL7850124 | 0.83 | KDM4E (0.49) | KDM4ELMNAHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677050-B1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVES | CHEIL JEDANG CORP (KR) | 2001-08-16 | — | — | EP | claimed |