Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | DPP4 | P27487 | 6/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838906 | 1.00 | KMT2A (0.56) | KMT2ADPP4CHRM2DRD1ALDH1A1 | |
| SCHEMBL10745216 | 0.89 | DPP4 (0.49) | KMT2ADPP4CHRM2DRD1ALDH1A1 | |
| SCHEMBL9647228 | 0.88 | DPP4 (0.53) | KMT2ADPP4CHRM2DRD1LMNA | |
| SCHEMBL7850682 | 0.88 | DPP4 (0.51) | KMT2ADPP4CHRM2DRD1ALDH1A1 | |
| SCHEMBL13576371 | 0.87 | KMT2A (0.69) | KMT2ADPP4CHRM2DRD1ALDH1A1 | |
| SCHEMBL9838735 | 0.87 | KMT2A (0.69) | KMT2ADPP4CHRM2DRD1ALDH1A1 | |
| SCHEMBL4575476 | 0.87 | KMT2A (0.69) | KMT2ADPP4CHRM2DRD1ALDH1A1 | |
| SCHEMBL10377709 | 0.87 | DPP4 (0.51) | KMT2ADPP4CHRM2DRD1ALDH1A1 | |
| SCHEMBL10749699 | 0.87 | DPP4 (0.50) | KMT2ADPP4CHRM2DRD1LMNA | |
| SCHEMBL9691077 | 0.87 | KCNH2 (0.53) | KMT2ADPP4CHRM2DRD1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235589-B1 | USE OF QUINOLONE AND NAPHTHYRIDINE ANTIBIOTICS FOR THE MANUFACTURE OF OPHTHALMIC MEDICAMENTS | WARNER-LAMBERT COMPANY (US) | 1992-10-28 | — | — | EP | claimed |
| EP-0187376-A2 | 6,7-Disubstituted 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids | BAYER AG (DE) | 1986-07-16 | — | — | EP | claimed |
| EP-0391169-A2 | Enantiomeric pure 7-(3-amino-1-pyrrolidinyl)-chinolon-and-naphthyridon carboxylic acids | BAYER AG (DE) | 1990-10-10 | — | — | EP | disclosed |
| EP-0268053-A1 | Metal salts of 1-cyclopropylquinolonecarboxylic acids and medicaments containing them | BAYER AG (DE) | 1988-05-25 | — | — | EP | disclosed |
| EP-0187376-A2 | 6,7-Disubstituted 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids | BAYER AG (DE) | 1986-07-16 | — | — | EP | disclosed |