Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 7/20 | 0.66 |
| ▸ | LCK | P06239 | 6/20 | 0.66 |
| ▸ | TEK | Q02763 | 5/20 | 0.66 |
| ▸ | BTK | Q06187 | 5/20 | 0.56 |
| ▸ | KDR | P35968 | 4/20 | 0.52 |
| ▸ | HCK | P08631 | 7/20 | 0.51 |
| ▸ | FLT3 | P36888 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852451 | 0.91 | LCK (0.66) | SRCLCKTEKBTKKDR | |
| SCHEMBL6461069 | 0.91 | SRC (0.62) | SRCLCKTEKBTKKDR | |
| SCHEMBL6461085 | 0.91 | SRC (0.62) | SRCLCKTEKBTKKDR | |
| SCHEMBL6461297 | 0.91 | SRC (0.62) | SRCLCKTEKBTKKDR | |
| SCHEMBL7854931 | 0.85 | LCK (0.67) | SRCLCKTEKBTKKDR | |
| SCHEMBL7855243 | 0.84 | SRC (0.68) | SRCLCKTEKBTKKDR | |
| SCHEMBL6458188 | 0.84 | LCK (0.60) | SRCLCKTEKBTKKDR | |
| SCHEMBL7852098 | 0.84 | SRC (0.67) | SRCLCKTEKBTKKDR | |
| SCHEMBL7851979 | 0.84 | LCK (0.65) | SRCLCKTEKBTKKDR | |
| SCHEMBL7842853 | 0.83 | LCK (0.64) | SRCLCKTEKBTKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114053-A1 | PYRROLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000017203-A1 | PYRROLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-30 | — | — | WO | disclosed |