Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.64 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854300 | 0.90 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL7851753 | 0.87 | AGTR1 (0.68) | AGTR1AGTR2PPARG | |
| SCHEMBL9704631 | 0.85 | AGTR1 (0.68) | AGTR1AGTR2PPARG | |
| SCHEMBL7850922 | 0.84 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9704754 | 0.84 | AGTR1 (0.69) | AGTR1AGTR2PPARG | |
| SCHEMBL9165966 | 0.82 | AGTR1 (0.67) | AGTR1AGTR2PPARG | |
| SCHEMBL9704873 | 0.81 | AGTR1 (0.74) | AGTR1AGTR2PPARG | |
| SCHEMBL7842666 | 0.81 | AGTR1 (0.77) | AGTR1AGTR2PPARG | |
| SCHEMBL7849966 | 0.81 | AGTR1 (0.70) | AGTR1AGTR2PPARG | |
| SCHEMBL7852666 | 0.81 | AGTR1 (0.70) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399731-B2 | Azaindenes | ASTRAZENECA AB (SE) | 2001-07-11 | — | — | EP | disclosed |
| EP-0399731-B1 | Azaindenes | ZENECA LTD (GB) | 1993-12-08 | — | — | EP | disclosed |
| EP-0399731-A1 | Azaindenes | ZENECA LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |