Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851241 | 0.87 | PIK3CG (0.33) | PIK3CGKDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL7851048 | 0.85 | PIK3CG (0.33) | PIK3CGKDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL9694523 | 0.84 | KDM4E (0.46) | PIK3CGKDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL7853924 | 0.82 | TOP2A (0.32) | ALDH1A1TOP2ATOP2B | |
| SCHEMBL7852426 | 0.82 | ALDH1A1 (0.35) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9416486 | 0.82 | DPP4 (0.34) | — | |
| Bromide SCHEMBL7851594 | 0.82 | ALDH1A1 (0.34) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7849739 | 0.82 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL7841322 | 0.79 | ALDH1A1 (0.33) | KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL9694106 | 0.78 | ALDH1A1 (0.42) | KDM4EALDH1A1LMNATOP2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726270-B1 | Derivatives of 1,6-naphthyridone carboxylic acids | BAYER AG (DE) | 2001-05-23 | — | — | EP | disclosed |
| EP-0726270-A1 | Derivatives of 1,6-naphthyridine carboxylic acids | BAYER AG (DE) | 1996-08-14 | — | — | EP | disclosed |