Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 9/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 9/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3142409 | 0.81 | PDE3B (0.39) | PDE3BPDE3AMAPTMEN1KMT2A | |
| SCHEMBL13524438 | 0.81 | PDE3B (0.41) | PDE3BPDE3AKDM4EALDH1A1MAPT | |
| SCHEMBL6398012 | 0.77 | SRD5A1 (0.49) | SRD5A1KDM4EALDH1A1XDHGABRA1 | |
| SCHEMBL9229963 | 0.76 | SRD5A1 (0.51) | SRD5A1PDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL7855008 | 0.76 | SRD5A1 (0.51) | SRD5A1KDM4EALDH1A1XDHGABRA1 | |
| SCHEMBL1400229 | 0.76 | SRD5A1 (0.40) | SRD5A1KDM4EALDH1A1XDHGABRA1 | |
| SCHEMBL8662012 | 0.74 | PDE3B (0.34) | PDE3BPDE3AKDM4EMEN1KMT2A | |
| SCHEMBL429173 | 0.74 | NPC1 (0.45) | PDE3BPDE3AKDM4EALDH1A1GABRA1 | |
| SCHEMBL9094062 | 0.74 | KDM4E (0.37) | SRD5A1KDM4EALDH1A1MAPTGAA | |
| SCHEMBL30690978 | 0.72 | PDE3B (0.46) | PDE3BPDE3AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719258-B1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5786367-A | OXYGEN SCAVENGERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| US-5576324-A | Quinoline derivatives or salt thereof and remedy for cardiac diseases containing the same | KOWA CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0638571-A1 | QUINOLINE DERIVATIVE OR SALT THEREOF AND REMEDY FOR CARDIAC DISEASES CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |