Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 8/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 8/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13524438 | 0.74 | PDE3B (0.41) | PDE3BPDE3AKDM4ELMNACYP1A2 | |
| SCHEMBL7853166 | 0.74 | SRD5A1 (0.43) | PDE3BPDE3AKDM4EMEN1LMNA | |
| SCHEMBL9229963 | 0.72 | SRD5A1 (0.51) | PDE3BPDE3AKDM4EMEN1PTGS2 | |
| SCHEMBL3142409 | 0.72 | PDE3B (0.39) | PDE3BPDE3AMEN1LMNAKMT2A | |
| SCHEMBL429173 | 0.63 | NPC1 (0.45) | PDE3BPDE3AKDM4EMEN1LMNA | |
| SCHEMBL3138016 | 0.62 | PDE3B (0.42) | PDE3BPDE3AKDM4ELMNACYP1A2 | |
| SCHEMBL12798630 | 0.61 | PPARD (0.33) | — | |
| SCHEMBL10818371 | 0.61 | PDE3B (0.65) | PDE3BPDE3A | |
| SCHEMBL9046052 | 0.60 | CA12 (0.35) | PDE3BPDE3AKDM4EMEN1CYP1A2 | |
| SCHEMBL9045968 | 0.60 | CA12 (0.40) | PDE3BPDE3AKDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786367-A | OXYGEN SCAVENGERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |