Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | GRM2 | Q14416 | 11/20 | 0.50 |
| ▸ | F10 | P00742 | 2/20 | 0.49 |
| ▸ | CALML3 | P27482 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7853568 | 1.00 | MAOA (0.51) | MAOAMAOBGRM2F10CALML3 | |
| SCHEMBL5384304 | 0.89 | F10 (0.57) | MAOAMAOBGRM2F10CALML3 | |
| SCHEMBL3327082 | 0.85 | MAOA (0.58) | MAOAMAOBGRM2F10CALML3 | |
| SCHEMBL3426022 | 0.85 | MAOA (0.58) | MAOAMAOBGRM2F10CALML3 | |
| SCHEMBL3323919 | 0.85 | MAOA (0.58) | MAOAMAOBGRM2F10CALML3 | |
| SCHEMBL4638737 | 0.83 | GRM2 (0.69) | MAOAMAOBGRM2 | |
| SCHEMBL12635778 | 0.83 | GRM2 (0.69) | MAOAMAOBGRM2 | |
| SCHEMBL1874998 | 0.83 | GRM2 (0.69) | MAOAMAOBGRM2 | |
| SCHEMBL9550251 | 0.78 | MAOA (0.59) | MAOAMAOBGRM2CALML3 | |
| SCHEMBL29348761 | 0.77 | TNKS (0.45) | MAOAMAOBF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082323-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AstraZeneca UK Limited (GB) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999064417-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 1999-12-16 | — | — | WO | disclosed |