SCHEMBL7854

SCHEMBL7854

c1cc2[nH]cncc-2n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27003885 0.98 CYP3A4 (0.42)
SCHEMBL20772034 0.98 CYP3A4 (0.42)
Pyridine SCHEMBL15874650 0.90 CYP3A4 (0.46)
Bicarbonate SCHEMBL28123369 0.90 KDM4C (0.41)
Azetidine SCHEMBL27493637 0.90 HRH3 (0.39)
Sulfamide SCHEMBL27407275 0.89 ASIC3 (0.38)
Phosphoric Acid SCHEMBL1880808 0.89 IDO1 (0.37)
Phenazine SCHEMBL28279302 0.87 IDO1 (0.43)
Piperidine SCHEMBL28092822 0.86 HRH3 (0.36)
Pyrazole SCHEMBL1611819 0.84 CYP3A4 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 20221 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4740010-A1 NEGATIVE TUNE STANDARD FOR MASS SPECTROMETRY Agilent Technologies, Inc. (US) 2026-05-13 EP claimed
CN-121394778-B Diaphragm and battery 珠海冠宇电池股份有限公司 2026-05-12 CN claimed
EP-3185329-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2026-04-22 EP claimed
US-12595297-B2 Methods and compositions for inhibition of EGF/EGFR pathway in combination with tyrosine kinase inhibitors IN3BIO LTD. (BM) 2026-04-07 US claimed
EP-4482583-B1 ZWITTERIONIC ANTIBACTERIAL COMPOUNDS HOFFMANN LA ROCHE (CH) 2026-04-01 EP claimed
US-12577554-B2 Methods for purification of messenger RNA TRANSLATE BIO, INC. (US) 2026-03-17 US claimed
EP-4705468-A1 MAMMALIAN POLYCISTRONIC EXPRESSION SYSTEM FOR DIRECT TRANSLATION FROM RNA AND SECRETION OF CARGO California Institute of Technology (US) 2026-03-11 EP claimed
US-12569572-B2 Messenger RNA therapy for the treatment of Friedreich's ataxia TRANSLATE BIO, INC. (US) 2026-03-10 US claimed
US-20260060970-A1 Use of a Therapeutic Agent with Phosphodiesterase-7 Inhibitory Activity for the Treatment and Prevention of Diseases Associated with Chronic Fatigue, Exhaustion and/or Exertional Intolerance MITODICURE GMBH (DE) 2026-03-05 US claimed
EP-4206205-B1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND PRIMEGENE BEIJING CO LTD (CN) 2026-03-04 EP claimed
WO-1994006438-A1 ADENOSINE ANALOGUES AND METHOD OF INCREASING ADENOSINE RELEASE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-03-31 WO claimed
US-5254687-A Process for the preparation of pyrrolo[2,3-d]pyrimidines THE TRUSTEES OF PRINCETON UNIVERSITY (US) 1993-10-19 US claimed
US-5216141-A OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR LINKAGES BENNER, STEVEN 1993-06-01 US claimed
EP-0530579-A1 Condensed pyrimidine derivatives antitumor agents Eisai Co., Ltd. (JP) 1993-03-10 EP claimed
EP-0418309-A4 OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR 1993-01-07 EP claimed
WO-1992012718-A1 ADENOSINE KINASE INHIBITORS GENSIA, INC. (US) 1992-08-06 WO claimed
EP-0418309-A1 OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR BENNER, Steven Albert (CH) 1991-03-27 EP claimed
WO-1989012060-A1 OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR BENNER STEVEN ALBERT (CH) 1989-12-14 WO claimed
EP-0071227-A1 Anti-leukemic beta-glycosyl C-nucleosides Sloan-Kettering Institute For Cancer Research (US) 1983-02-09 EP claimed
US-4140851-A Synthesis and antitumor activity of 2,4,5-trisubstituted-pyrrolo2,3-d]-pyrimidine nucleosides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1979-02-20 US claimed