⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7853420 | 0.96 | HRH4 (0.32) | — | |
| SCHEMBL2766033 | 0.94 | HAO1 (0.33) | — | |
| SCHEMBL7853197 | 0.94 | HAO1 (0.33) | — | |
| SCHEMBL7853485 | 0.94 | HAO1 (0.33) | — | |
| SCHEMBL1558449 | 0.85 | SLC18A3 (0.38) | — | |
| SCHEMBL23631114 | 0.82 | ESR2 (0.34) | — | |
| SCHEMBL20599464 | 0.70 | KCNH2 (0.31) | — | |
| SCHEMBL16799731 | 0.65 | JAK2 (0.34) | — | |
| SCHEMBL12478452 | 0.61 | — | — | |
| SCHEMBL7845471 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013086397-A1 | UREA COMPOUNDS AS GKA ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2013-06-13 | — | — | WO | claimed |
| EP-0719258-B1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5786367-A | OXYGEN SCAVENGERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0719258-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
| WO-1996002508-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-01 | — | — | WO | disclosed |