Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 5/20 | 0.45 |
| ▸ | CTSB | P07858 | 3/20 | 0.45 |
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862112 | 0.95 | SYK (0.46) | SYKCA2CA5ACTSKCTSB | |
| SCHEMBL7862146 | 0.92 | CYP3A4 (0.52) | SYKCA2CA5ACTSKCTSB | |
| SCHEMBL7860507 | 0.88 | CA2 (0.52) | CA2CA5ACTSKCTSBCTSL | |
| SCHEMBL7862070 | 0.87 | CA2 (0.48) | CA2CA5ACTSKCTSBCTSL | |
| SCHEMBL3736788 | 0.83 | SYK (0.50) | SYKCTSKCTSBCTSLCASP1 | |
| SCHEMBL28870540 | 0.83 | SYK (0.50) | SYKCTSKCTSBCTSLCASP1 | |
| SCHEMBL24131771 | 0.82 | SYK (0.49) | SYKCTSKCTSBCTSLCASP1 | |
| SCHEMBL3727297 | 0.81 | CA2 (0.53) | CA2CA5ACTSKCTSBCTSL | |
| SCHEMBL23748811 | 0.81 | SYK (0.48) | SYKCTSKCTSBCTSLCASP1 | |
| SCHEMBL23748810 | 0.81 | SYK (0.48) | SYKCTSKCTSBCTSLCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121366-A1 | PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS | MEDIVIR AB (SE) | 2001-08-08 | — | — | EP | disclosed |
| WO-1999051613-A1 | PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS | MEDIVIR AB (SE) | 1999-10-14 | — | — | WO | disclosed |