⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14459984 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL5229992 | 0.97 | EPHX1 (0.38) | — | |
| SCHEMBL24503675 | 0.89 | EPHX1 (0.43) | — | |
| SCHEMBL5547123 | 0.83 | ADH1B (0.32) | — | |
| SCHEMBL1073021 | 0.83 | — | — | |
| SCHEMBL15522382 | 0.83 | ADH1B (0.32) | — | |
| SCHEMBL24057912 | 0.82 | EPHX1 (0.37) | — | |
| SCHEMBL12399545 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL270943 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL16716874 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253785-A2 | IMPROVED PROSTATE-SPECIFIC MEMBRANE ANTIGEN TARGETING RADIOPHARMACEUTICALS AND USES THEREOF | Universität Heidelberg (DE) | 2022-12-08 | — | — | WO | disclosed |
| EP-3388419-A1 | GLI1 INHIBITORS AND USES THEREOF | Leadiant Biosciences SA (CH) | 2018-10-17 | — | — | EP | disclosed |
| CN-1264843-C | Pyrazolopyrimidinone derivatives having PDE7 inhibitory action | DAIICHI SUNTORY PHARMACEUTICAL (JP) | 2006-07-19 | — | — | CN | disclosed |
| CN-1533392-A | Pyrazolopgrimidinone derivatives having PED 7 inhibitory activity | ��һ��������ҩ��ʽ���� | 2004-09-29 | — | — | CN | disclosed |
| EP-1144403-A1 | SUBSTITUED PYRAZOLES AS P38 KINASE INHIBITORS | G.D. SEARLE & CO. (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000031063-A1 | SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS | G.D. SEARLE & CO. (US) | 2000-06-02 | — | — | WO | disclosed |