Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3146987 | 1.00 | MAPK1 (0.52) | MAPK1L3MBTL1GBA1GRM2PRKCD | |
| SCHEMBL1712313 | 0.98 | MAPK1 (0.51) | MAPK1L3MBTL1GBA1GRM2PRKCD | |
| SCHEMBL1712309 | 0.98 | MAPK1 (0.51) | MAPK1L3MBTL1GBA1GRM2PRKCD | |
| SCHEMBL9492421 | 0.95 | L3MBTL1 (0.57) | MAPK1L3MBTL1GBA1GRM2MAOA | |
| SCHEMBL15757516 | 0.88 | MAPK1 (0.46) | MAPK1L3MBTL1GRM2MAOAMAOB | |
| SCHEMBL9228870 | 0.88 | MAPK1 (0.46) | MAPK1L3MBTL1GRM2MAOAMAOB | |
| SCHEMBL9226555 | 0.88 | MAPK1 (0.46) | MAPK1L3MBTL1GRM2MAOAMAOB | |
| SCHEMBL11077247 | 0.84 | MAPK1 (0.52) | MAPK1L3MBTL1GBA1GRM2 | |
| SCHEMBL15796775 | 0.84 | MAPK1 (0.52) | MAPK1L3MBTL1GBA1GRM2 | |
| SCHEMBL21253882 | 0.84 | GRM2 (0.56) | MAPK1L3MBTL1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1130016-A1 | THIOCARBAMIC ACID DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-09-05 | — | — | EP | disclosed |