Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852895 | 0.82 | CARM1 (0.42) | GNAI3GNAO1GNAI1 | |
| SCHEMBL7118557 | 0.81 | — | — | |
| SCHEMBL20072865 | 0.80 | GNAI3 (0.36) | GNAI3GNAO1GNAI1 | |
| SCHEMBL7854064 | 0.80 | GNAI3 (0.36) | GNAI3GNAO1GNAI1 | |
| SCHEMBL8778709 | 0.80 | GNAI3 (0.45) | GNAI3GNAO1GNAI1 | |
| SCHEMBL20000752 | 0.80 | — | — | |
| SCHEMBL7856674 | 0.77 | — | — | |
| SCHEMBL3326166 | 0.75 | — | — | |
| SCHEMBL28503023 | 0.75 | — | — | |
| SCHEMBL7851739 | 0.74 | GNAI3 (0.38) | GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144403-A1 | SUBSTITUED PYRAZOLES AS P38 KINASE INHIBITORS | G.D. SEARLE & CO. (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000031063-A1 | SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS | G.D. SEARLE & CO. (US) | 2000-06-02 | — | — | WO | disclosed |