Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 16/20 | 0.78 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180123 | 0.90 | GHSR (0.69) | GHSRSCN9APOLB | |
| SCHEMBL6177479 | 0.88 | GHSR (1.00) | GHSRSCN9APOLB | |
| SCHEMBL6179529 | 0.86 | GHSR (0.79) | GHSRSCN9APOLB | |
| SCHEMBL6181060 | 0.86 | GHSR (0.62) | GHSRSCN9APOLB | |
| SCHEMBL6180076 | 0.85 | GHSR (0.76) | GHSRSCN9APOLB | |
| SCHEMBL7857877 | 0.84 | GHSR (0.58) | GHSRSCN9A | |
| SCHEMBL6180568 | 0.84 | GHSR (0.61) | GHSRSCN9APOLB | |
| SCHEMBL6178405 | 0.83 | GHSR (0.71) | GHSRSCN9APOLB | |
| SCHEMBL6179661 | 0.83 | GHSR (0.65) | GHSRSCN9A | |
| SCHEMBL7840414 | 0.83 | GHSR (0.63) | GHSRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105376-A1 | OXINDOLE DERIVATIVES AS GROWTH HORMONE RELEASERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010975-A1 | OXINDOLE DERIVATIVES AS GROWTH HORMONE RELEASERS | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2000-03-02 | — | — | WO | disclosed |