Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 5/20 | 0.56 |
| ▸ | BLM | P54132 | 3/20 | 0.56 |
| ▸ | NSD2 | O96028 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11119733 | 1.00 | MEN1 (0.56) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL7845898 | 1.00 | MEN1 (0.56) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL11865193 | 1.00 | MEN1 (0.56) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL1908099 | 1.00 | MEN1 (0.56) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL30097103 | 0.98 | MEN1 (0.58) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL439386 | 0.98 | MEN1 (0.58) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL156500 | 0.93 | MEN1 (0.59) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL29364149 | 0.93 | MEN1 (0.59) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL29368479 | 0.93 | MEN1 (0.59) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL13587212 | 0.93 | TOP2B (0.59) | MEN1KMT2APOLBBLMNSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3960751-A | LIQUID CRYSTAL | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) | 1976-06-01 | — | — | US | claimed |
| US-6210783-B1 | COMPRISED OF SUPPORTING SUBSTRATE, A HEAT DISSIPATING COATING LAYER IN CONTACT WITH SUBSTRATE, WHEREIN COATING IS COMPRISED OF A HEAT DISSIPATING BINDER, AN ANTISTATIC COMPOUND, AN INK RECEIVER COATING COMPRISING BINDER, OXAZOLINE COMPOUND | XEROX CORPORATION | 2001-04-03 | — | — | US | disclosed |
| US-5436243-A | Aminoanthraquinone derivatives to combat multidrug resistance | RESEARCH TRIANGLE INSTITUTE DUKE UNIVERSITY (US) | 1995-07-25 | — | — | US | disclosed |
| WO-1995013813-A1 | AMINOANTHRAQUINONE DERIVATIVES TO COMBAT MULTIDRUG RESISTANCE | DUKE UNIVERSITY (US) | 1995-05-26 | — | — | WO | disclosed |