Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.62 |
| ▸ | CYP17A1 | P05093 | 8/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8156789 | 0.83 | CYP19A1 (0.66) | CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL8149595 | 0.83 | CYP19A1 (0.66) | CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL9784379 | 0.83 | CYP19A1 (0.66) | CYP19A1CYP17A1 | |
| SCHEMBL1507993 | 0.81 | CYP19A1 (0.67) | CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL7859488 | 0.81 | CYP19A1 (0.67) | CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL1507781 | 0.80 | CYP19A1 (0.66) | CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL9167130 | 0.80 | CYP19A1 (0.66) | CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL1508005 | 0.79 | CYP19A1 (0.69) | CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL8142992 | 0.77 | CYP19A1 (0.56) | CYP19A1CYP17A1 | |
| SCHEMBL3364270 | 0.77 | CYP17A1 (0.44) | CYP19A1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007051-A1 | PRENYL-PROTEIN TRANSFERASE INHIBITORS | MERCK & CO., INC. (US) | 2001-02-01 | — | — | WO | disclosed |