Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 6/20 | 0.47 |
| ▸ | CCND1 | P24385 | 6/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | SNCA | P37840 | 3/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7223277 | 0.86 | F10 (0.52) | CDK4CCND1SNCATRPV1F10 | |
| SCHEMBL7224324 | 0.86 | CDK4 (0.47) | CDK4CCND1SNCATRPV1F10 | |
| SCHEMBL7224765 | 0.84 | MAPT (0.51) | CDK4CCND1PPARGSNCATRPV1 | |
| SCHEMBL7224079 | 0.83 | LTA4H (0.54) | CDK4CCND1SNCATRPV1F10 | |
| SCHEMBL7225358 | 0.83 | SNCA (0.52) | CDK4CCND1SNCATRPV1F10 | |
| SCHEMBL7222947 | 0.83 | SNCA (0.60) | SNCAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7224360 | 0.82 | KMT2A (0.47) | CDK4CCND1SNCATRPV1F10 | |
| SCHEMBL7231033 | 0.82 | SNCA (0.45) | CDK4CCND1SNCATRPV1F10 | |
| SCHEMBL7230814 | 0.82 | HRH3 (0.44) | SNCATRPV1ACHELMNAL3MBTL1 | |
| SCHEMBL7225859 | 0.82 | F10 (0.54) | CDK4CCND1SNCATRPV1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140901-A2 | SUBSTITUTED (AMINOIMINOMETHYL OR AMINOMETHYL)BENZOHETEROARYL COMPOUNDS AS FACTOR XA INHIBITORS | Aventis Pharmaceuticals Products Inc. (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000039087-A2 | SUBSTITUTED (AMINOIMINOMETHYL OR AMINOMETHYL)BENZOHETEROARYL COMPOUNDS AS FACTOR XA INHIBITORS | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 2000-07-06 | — | — | WO | claimed |