SCHEMBL7857412

SCHEMBL7857412

CCC(COC(=O)c1ccccc1C(=O)OCC(CC)CC(C)C)CC(C)C

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.67
TSHR P16473 7/20 0.67
CYP3A4 P08684 2/20 0.66
CA2 P00918 1/20 0.66
PRSS1 P07477 1/20 0.62
PRSS2 P07478 1/20 0.62
PRSS3 P35030 1/20 0.62
LMNA P02545 2/20 0.56
MAPK1 P28482 2/20 0.48
TDP1 Q9NUW8 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TP53 P04637 2/20 0.46
HSD17B10 Q99714 1/20 0.46
MAPT P10636 2/20 0.45
NPC1 O15118 1/20 0.45
HTT P42858 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MEN1 O00255 1/20 0.44
NPY1R P25929 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29368000 0.88 ALDH1A1 (0.76) ALDH1A1TSHRCYP3A4CA2PRSS1
SCHEMBL420283 0.88 ALDH1A1 (0.76) ALDH1A1TSHRCYP3A4CA2PRSS1
SCHEMBL7749197 0.86 ALDH1A1 (0.56) ALDH1A1TSHRCYP3A4CA2PRSS1
SCHEMBL5366495 0.83 MAPT (0.57) ALDH1A1TSHRCYP3A4CA2PRSS1
SCHEMBL3775482 0.82 ALDH1A1 (0.68) ALDH1A1TSHRCYP3A4CA2PRSS1
SCHEMBL4362343 0.82 ALDH1A1 (0.82) ALDH1A1TSHRCYP3A4CA2PRSS1
SCHEMBL3685226 0.81 ALDH1A1 (0.73) ALDH1A1TSHRCYP3A4CA2PRSS1
Diethyl Phthalate SCHEMBL5152078 0.81 ALDH1A1 (0.86) ALDH1A1TSHRCYP3A4CA2PRSS1
SCHEMBL1142993 0.81 ALDH1A1 (0.86) ALDH1A1TSHRCYP3A4CA2PRSS1
SCHEMBL27218092 0.81 ALDH1A1 (0.71) ALDH1A1TSHRCYP3A4CA2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2001123009-A PLASTICIZER AND POLYVINYL CHLORIDE-BASED COMPOSITION CONTAINING THE SAME MITSUBISHI CHEMICALS CORP 2001-05-08 JP disclosed
US-4426542-A HYDROFORMYLATION, ALDOL CONDENSATION, HYDROGENATION MONSANTO COMPANY (US) 1984-01-17 US disclosed
EP-0094456-A1 Preparation of alcohols from olefins having from 3 to 7 carbon atoms MONSANTO COMPANY (US) 1983-11-23 EP disclosed