Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 7/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 9/20 | 0.41 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SDHA | P31040 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7857432 | 1.00 | CALML3 (0.50) | CALML3CYP3A4CYP2C9MAOAMAOB | |
| SCHEMBL7082551 | 0.96 | MAOA (0.43) | CALML3CYP3A4CYP2C9MAOAMAOB | |
| SCHEMBL7082548 | 0.96 | MAOA (0.43) | CALML3CYP3A4CYP2C9MAOAMAOB | |
| SCHEMBL8111357 | 0.87 | CALML3 (0.64) | CALML3CYP3A4CYP2C9MAOAMAOB | |
| SCHEMBL5832691 | 0.87 | CALML3 (0.64) | CALML3CYP3A4CYP2C9MAOAMAOB | |
| SCHEMBL5832684 | 0.87 | CALML3 (0.64) | CALML3CYP3A4CYP2C9MAOAMAOB | |
| SCHEMBL7077051 | 0.84 | MAOA (0.42) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL7077047 | 0.84 | MAOA (0.42) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL7078471 | 0.82 | MAOA (0.46) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL7078474 | 0.82 | MAOA (0.46) | CALML3MAOAMAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082323-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AstraZeneca UK Limited (GB) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999064417-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 1999-12-16 | — | — | WO | disclosed |