Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 14/20 | 0.58 |
| ▸ | SELE | P16581 | 14/20 | 0.58 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.58 |
| ▸ | CDK8 | P49336 | 4/20 | 0.58 |
| ▸ | CCNC | P24863 | 3/20 | 0.58 |
| ▸ | CDK9 | P50750 | 2/20 | 0.58 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.58 |
| ▸ | DAPK3 | O43293 | 4/20 | 0.48 |
| ▸ | PIM1 | P11309 | 4/20 | 0.48 |
| ▸ | PRKACA | P17612 | 4/20 | 0.48 |
| ▸ | KDR | P35968 | 4/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.48 |
| ▸ | GSK3A | P49840 | 4/20 | 0.48 |
| ▸ | GSK3B | P49841 | 4/20 | 0.48 |
| ▸ | LIMK1 | P53667 | 4/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.48 |
| ▸ | PLK4 | O00444 | 3/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.48 |
| ▸ | CDK1 | P06493 | 3/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7855367 | 0.85 | CCNC (0.61) | ICAM1SELEVCAM1CDK8CCNC | |
| SCHEMBL7250679 | 0.80 | ICAM1 (0.66) | ICAM1SELEVCAM1CDK8CCNC | |
| SCHEMBL7642734 | 0.78 | ICAM1 (0.64) | ICAM1SELEVCAM1CDK8CCNC | |
| SCHEMBL7055360 | 0.76 | PIM1 (0.76) | ICAM1SELEVCAM1CDK8CCNC | |
| SCHEMBL7054697 | 0.73 | ICAM1 (1.00) | ICAM1SELEVCAM1CDK8CCNC | |
| SCHEMBL7055361 | 0.73 | ICAM1 (1.00) | ICAM1SELEVCAM1CDK8CCNC | |
| SCHEMBL7055169 | 0.73 | ICAM1 (1.00) | ICAM1SELEVCAM1CDK8CCNC | |
| SCHEMBL7058163 | 0.73 | ICAM1 (1.00) | ICAM1SELEVCAM1CDK8CCNC | |
| SCHEMBL7058161 | 0.72 | ICAM1 (0.59) | ICAM1SELEVCAM1CDK8CCNC | |
| Formamide SCHEMBL7052564 | 0.72 | PIM1 (0.70) | ICAM1SELEVCAM1CDK8CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090009-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999062908-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 1999-12-09 | — | — | WO | disclosed |