Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 10/20 | 0.60 |
| ▸ | MC3R | P41968 | 7/20 | 0.60 |
| ▸ | MC5R | P33032 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MC1R | Q01726 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358504 | 1.00 | MC4R (0.60) | MC4RMC3RMC5RKDM4EALDH1A1 | |
| SCHEMBL7857073 | 0.91 | MC4R (0.49) | MC4RMC3RMC5RKDM4EALDH1A1 | |
| SCHEMBL7857113 | 0.91 | MC4R (0.49) | MC4RMC3RMC5RKDM4EALDH1A1 | |
| SCHEMBL8360637 | 0.87 | MC4R (0.52) | MC4RMC3RMC5RKDM4EALDH1A1 | |
| SCHEMBL8360633 | 0.87 | MC4R (0.52) | MC4RMC3RMC5RKDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7850378 | 0.82 | MC4R (0.47) | MC4RMC3RMC5RKDM4EALDH1A1 | |
| SCHEMBL7857869 | 0.80 | MC4R (0.53) | MC4RMC3RMC5RMC1R | |
| SCHEMBL7857873 | 0.80 | MC4R (0.53) | MC4RMC3RMC5RMC1R | |
| SCHEMBL7850336 | 0.76 | MC4R (0.54) | MC4RMC3RMC5RKDM4EALDH1A1 | |
| SCHEMBL9269541 | 0.74 | KDM4E (0.57) | KDM4EALDH1A1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |