Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 6/20 | 0.47 |
| ▸ | MC3R | P41968 | 5/20 | 0.47 |
| ▸ | MC5R | P33032 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MC1R | Q01726 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8360637 | 0.94 | MC4R (0.52) | MC4RMC3RMC5RKDM4EALDH1A1 | |
| SCHEMBL8360633 | 0.94 | MC4R (0.52) | MC4RMC3RMC5RKDM4EALDH1A1 | |
| SCHEMBL7857073 | 0.87 | MC4R (0.49) | MC4RMC3RMC5RKDM4EALDH1A1 | |
| SCHEMBL7857113 | 0.87 | MC4R (0.49) | MC4RMC3RMC5RKDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7857975 | 0.84 | MC4R (0.48) | MC4RMC3RMC5R | |
| SCHEMBL7857808 | 0.82 | MC4R (0.60) | MC4RMC3RMC5RKDM4EALDH1A1 | |
| SCHEMBL8358504 | 0.82 | MC4R (0.60) | MC4RMC3RMC5RKDM4EALDH1A1 | |
| SCHEMBL7857827 | 0.78 | MC4R (0.51) | MC4RMC3RMC5R | |
| Trifluoroacetic Acid SCHEMBL8170100 | 0.76 | LTA4H (0.41) | MC4RMC3RPPARGPPARDPPARA | |
| SCHEMBL8175656 | 0.74 | MC4R (0.36) | MC4RMC3RMC5RKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| US-6114310-A | THERAPY FOR MICROBIAL INFECTIONS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-09-05 | — | — | US | disclosed |