Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3050230 | 0.78 | MEN1 (0.46) | KDM4ECYP1A2MEN1KMT2APOLB | |
| SCHEMBL7730448 | 0.77 | HDAC1 (0.45) | MEN1KMT2APOLBL3MBTL1RAB9A | |
| SCHEMBL19339522 | 0.76 | HPGD (0.50) | PSMB5ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3635901 | 0.76 | LTA4H (0.56) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL22421882 | 0.74 | MEN1 (0.49) | MEN1KMT2APOLBL3MBTL1RAB9A | |
| SCHEMBL9823156 | 0.74 | HDAC1 (0.54) | MEN1KMT2AMAPTL3MBTL1RAB9A | |
| SCHEMBL4781274 | 0.74 | HDAC3 (0.48) | ALDH1A1KDM4ECYP1A2MEN1KMT2A | |
| SCHEMBL7860788 | 0.73 | MC4R (0.48) | PSMB5ALDH1A1KDM4ECYP1A2MEN1 | |
| SCHEMBL6717933 | 0.73 | LTA4H (0.58) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL4367428 | 0.73 | AKT1 (0.48) | ALDH1A1KDM4ECYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| US-6114310-A | THERAPY FOR MICROBIAL INFECTIONS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-09-05 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |