Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 4/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7857968 | 0.83 | KDM4E (0.45) | KDM4EALDH1A1HPGDALOX15CDC25B | |
| SCHEMBL22967441 | 0.80 | POLB (0.39) | KDM4EALDH1A1HPGDCDC25BMEN1 | |
| SCHEMBL443362 | 0.76 | NQO1 (0.57) | KDM4EALDH1A1HPGDCDC25BNQO1 | |
| SCHEMBL29370537 | 0.76 | NQO1 (0.57) | KDM4EALDH1A1HPGDCDC25BNQO1 | |
| SCHEMBL8169209 | 0.75 | CA12 (0.52) | KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL1896897 | 0.75 | KMT2A (0.56) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7857849 | 0.74 | NQO1 (0.55) | KDM4EALDH1A1HPGDALOX15CDC25B | |
| SCHEMBL23043732 | 0.74 | ELANE (0.43) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL28317882 | 0.74 | NCEH1 (0.36) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL4082182 | 0.73 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| US-6114310-A | THERAPY FOR MICROBIAL INFECTIONS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-09-05 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |