Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27932882 | 0.81 | MAOB (0.36) | NPC1RAB9AALDH1A1LMNAMAOA | |
| SCHEMBL5131865 | 0.81 | HDAC1 (0.35) | NPC1RAB9AALDH1A1LMNASIGMAR1 | |
| SCHEMBL5671293 | 0.78 | NPC1 (0.37) | NPC1RAB9AALDH1A1LMNAHPGD | |
| SCHEMBL28926102 | 0.77 | HDAC4 (0.32) | NPC1RAB9AALDH1A1LMNAHPGD | |
| SCHEMBL8957775 | 0.76 | HDAC1 (0.37) | NPC1RAB9AALDH1A1LMNAHPGD | |
| SCHEMBL2712667 | 0.76 | NPC1 (0.36) | NPC1RAB9AALDH1A1LMNAHPGD | |
| SCHEMBL16796978 | 0.76 | NPC1 (0.33) | NPC1RAB9AALDH1A1LMNAHPGD | |
| SCHEMBL3266268 | 0.76 | NPC1 (0.40) | NPC1RAB9AALDH1A1LMNAHPGD | |
| Methane SCHEMBL28000918 | 0.76 | NPC1 (0.36) | NPC1RAB9AALDH1A1LMNAHPGD | |
| SCHEMBL30679293 | 0.76 | NPC1 (0.30) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103874697-A | Dibenzooxepin derivative | KYOWA HAKKO KIRIN CO LTD | 2014-06-18 | — | — | CN | disclosed |
| US-6197217-B1 | EXHIBIT A NEGATIVE DIELECTRIC ANISOTROPY VALUE, HAVE AN EXTREMELY HIGH VOLTAGE HOLDING RATIO AND A LOW THRESHOLD VOLTAGE, SMALL DEPENDENCY ON TEMPERATURE, HARDLY EXHIBIT SMECTIC PHASE; EXCELLENT IN MISCIBILITY WITH OTHER LC'S | CHISSO CORPORATION (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0959061-A1 | 3,3'-DIFLUOROBIPHENYL DERIVATIVES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY ELEMENTS | CHISSO CORPORATION (JP) | 1999-11-24 | — | — | EP | disclosed |
| US-5061669-A | Catalyst comprising anhydrous nickel compound, bidentate phosphorus-containing ligand, reducing metal | EASTMAN KODAK COMPANY (US) | 1991-10-29 | — | — | US | disclosed |
| US-4916227-A | From aromatic halide using coordinating catalyst containing nickel, phosphorus containing ligand, and reducing metal | EASTMAN KODAK COMPANY (US) | 1990-04-10 | — | — | US | disclosed |