Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957775 | 0.81 | HDAC1 (0.37) | HDAC1HDAC2SIGMAR1NPC1RAB9A | |
| SCHEMBL7858112 | 0.81 | NPC1 (0.33) | HDAC1HDAC2SIGMAR1NPC1RAB9A | |
| SCHEMBL27897540 | 0.80 | HDAC1 (0.41) | HDAC1HDAC2NPC1RAB9AALDH1A1 | |
| Methane SCHEMBL28875106 | 0.79 | HDAC1 (0.36) | HDAC1HDAC2NPC1RAB9AALDH1A1 | |
| SCHEMBL28737740 | 0.78 | HRH3 (0.39) | — | |
| SCHEMBL27932882 | 0.78 | MAOB (0.36) | NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL5067245 | 0.78 | HDAC1 (0.35) | HDAC1HDAC2NPC1RAB9AALDH1A1 | |
| SCHEMBL28926102 | 0.77 | HDAC4 (0.32) | NPC1RAB9AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL5072257 | 0.76 | HDAC1 (0.34) | HDAC1HDAC2HTR2CNPC1RAB9A | |
| SCHEMBL28658397 | 0.75 | HDAC1 (0.33) | HDAC1HDAC2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110194746-B | Compound for treating alzheimer disease, preparation method and application thereof | 云南大学 | 2022-11-18 | — | — | CN | disclosed |
| EP-1957493-A1 | 8-AZABICYCLO[3.2.1]OCTANE DERIVATIVES USEFUL AS MONOAMINE REUPTAKE INHIBITORS | N.V. Organon (NL) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063071-A1 | 8-AZABICYCLO[3.2.1]OCTANE DERIVATIVES USEFUL AS MONOAMINE REUPTAKE INHIBITORS | N.V. ORGANON (NL) | 2007-06-07 | — | — | WO | disclosed |