Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860563 | 0.88 | DPP8 (0.40) | DPP8DPP9ATMTDP1PLCG1 | |
| SCHEMBL7860707 | 0.86 | DPP8 (0.40) | DPP8DPP9ATMTGM2L3MBTL1 | |
| SCHEMBL8583297 | 0.86 | DPP8 (0.40) | DPP8DPP9ATMTGM2L3MBTL1 | |
| SCHEMBL7854735 | 0.86 | DPP8 (0.36) | DPP8DPP9ATMCTSLTDP1 | |
| SCHEMBL7859725 | 0.85 | DPP8 (0.37) | DPP8DPP9CTSLTDP1PLCG1 | |
| SCHEMBL7858354 | 0.85 | DPP8 (0.37) | DPP8DPP9ATMCTSLTDP1 | |
| SCHEMBL7858359 | 0.84 | DPP8 (0.38) | DPP8DPP9ATMTGM2L3MBTL1 | |
| SCHEMBL7861468 | 0.81 | ATM (0.42) | ATMTDP1RAB9A | |
| SCHEMBL8107953 | 0.81 | DPP8 (0.45) | DPP8DPP9ATMCTSLTDP1 | |
| SCHEMBL7859920 | 0.80 | ABCB1 (0.40) | DPP8DPP9ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747381-B1 | CARBAPENEM DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| EP-0747381-A1 | CARBAPENEM DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |