Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859221 | 0.90 | ATM (0.38) | ATMTDP1HTR2AALDH1A1MAPT | |
| SCHEMBL7860707 | 0.88 | DPP8 (0.40) | ATMALDH1A1MAPTHPGD | |
| SCHEMBL8583297 | 0.88 | DPP8 (0.40) | ATMALDH1A1MAPTHPGD | |
| SCHEMBL7858354 | 0.86 | DPP8 (0.37) | ATMTDP1ALDH1A1MAPTHPGD | |
| SCHEMBL7858359 | 0.86 | DPP8 (0.38) | ATMALDH1A1MAPTHPGD | |
| SCHEMBL7804746 | 0.84 | ALDH1A1 (0.39) | ATMTDP1HTR2ACCR5ALDH1A1 | |
| SCHEMBL7799275 | 0.84 | ALDH1A1 (0.39) | ATMTDP1HTR2ACCR5ALDH1A1 | |
| SCHEMBL7860059 | 0.83 | ATM (0.46) | ATMTDP1RAB9ACCR5ALDH1A1 | |
| SCHEMBL10520181 | 0.82 | ALDH1A1 (0.36) | ATMTDP1HTR2ACCR5ALDH1A1 | |
| SCHEMBL9728021 | 0.82 | ATM (0.43) | ATMTDP1HTR2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747381-B1 | CARBAPENEM DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5707987-A | BACTERICIDE ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0747381-A1 | CARBAPENEM DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |