Sugi Predict

Sugi Predict / Compounds / SCHEMBL7858808

SCHEMBL7858808

SCHEMBL7858808

Cc1noc(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ EDNRA P25101 17/20 1.00
▸ EDNRB P24530 12/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9063692 0.87 EDNRA (1.00) EDNRAEDNRB
SCHEMBL7221462 0.87 EDNRA (1.00) EDNRAEDNRB
SCHEMBL7857530 0.80 EDNRA (1.00) EDNRAEDNRB
SCHEMBL7860462 0.80 EDNRA (1.00) EDNRAEDNRB
SCHEMBL7857604 0.79 EDNRA (0.76) EDNRAEDNRB
SCHEMBL7857285 0.77 EDNRA (1.00) EDNRAEDNRB
SCHEMBL7221804 0.76 EDNRA (1.00) EDNRAEDNRB
SCHEMBL7716759 0.76 EDNRA (1.00) EDNRAEDNRB
SCHEMBL7858820 0.76 EDNRA (0.79) EDNRAEDNRB
SCHEMBL24823800 0.76 EDNRA (0.71) EDNRAEDNRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1069114-A2 Sulfonamides and derivatives thereof that modulate the activity of endothelin TEXAS BIOTECHNOLOGY CORPORATION (US) 2001-01-17 — — EP disclosed