SCHEMBL7858898

SCHEMBL7858898

NCC(=O)N(C[C]=O)C[C]=O

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GLRA1 P23415 1/20 0.32
SLC6A9 P48067 1/20 0.32
OR51E2 Q9H255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3115290 0.86 LMNA (0.38)
SCHEMBL7748147 0.83 CA12 (0.39)
SCHEMBL3928512 0.77 DPP4 (0.41) GLRA1SLC6A9OR51E2
SCHEMBL7747995 0.75 KDM4E (0.49)
SCHEMBL582879 0.75
SCHEMBL1521344 0.72 CHRM1 (0.39)
SCHEMBL7746730 0.70
SCHEMBL7749782 0.70 GAA (0.34)
SCHEMBL18322817 0.70
SCHEMBL8605865 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0751779-B1 SELECTIVELY CLEAVABLE LINKERS BASED ON IMINODIACETIC ACID ESTER BONDS SELECTIDE CORP (US) 2001-12-19 EP claimed
EP-0751779-A4 SELECTIVELY CLEAVABLE LINKERS BASED ON IMINODIACETIC ACID ESTER BONDS SELECTIDE CORP (US) 1998-12-09 EP claimed
EP-0751779-A1 SELECTIVELY CLEAVABLE LINKERS BASED ON IMINODIACETIC ACID ESTER BONDS SELECTIDE CORPORATION (US) 1997-01-08 EP claimed
WO-1995000165-A1 SELECTIVELY CLEAVABLE LINKERS BASED ON IMINODIACETIC ACID ESTER BONDS SELECTIDE CORPORATION (US) 1995-01-05 WO claimed