Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.42 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.38 |
| ▸ | PEPD | P12955 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859308 | 1.00 | GRM6 (0.42) | GRM6GRM2GRM3ACEF2 | |
| SCHEMBL7859310 | 1.00 | GRM6 (0.42) | GRM6GRM2GRM3ACEF2 | |
| SCHEMBL31630212 | 0.85 | TSHR (0.43) | RAB9AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL31629893 | 0.85 | TSHR (0.43) | RAB9AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL7311871 | 0.81 | SMN1; SMN2 (0.44) | RAB9AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL7311878 | 0.81 | SMN1; SMN2 (0.44) | RAB9AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL7311882 | 0.81 | SMN1; SMN2 (0.44) | RAB9AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL7308764 | 0.78 | SMN1; SMN2 (0.47) | RAB9AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL11001751 | 0.76 | ACE (0.65) | ACEMAPTLMNARAB9AGAA | |
| SCHEMBL1496672 | 0.76 | TSHR (0.46) | GRM6GRM2GRM3F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937036-B1 | SUBSTITUTED 4-BIPHENYL-4-HYDROXYBUTYRIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITORS | BAYER AG (US) | 2001-12-05 | — | — | EP | disclosed |