⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18541270 | 1.00 | — | — | |
| SCHEMBL24021305 | 1.00 | — | — | |
| SCHEMBL21461380 | 0.80 | — | — | |
| SCHEMBL17234241 | 0.80 | — | — | |
| SCHEMBL580048 | 0.78 | — | — | |
| SCHEMBL28066827 | 0.78 | — | — | |
| SCHEMBL17234155 | 0.76 | ECE1 (0.43) | — | |
| Hydrochloric Acid SCHEMBL11809895 | 0.76 | CTH (0.41) | — | |
| Hydrochloric Acid SCHEMBL11809897 | 0.76 | CTH (0.41) | — | |
| SCHEMBL10752337 | 0.76 | ECE1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793646-B1 | AMINOGUANIDINE CARBOXYLATES FOR THE TREATMENT OF NON-INSULIN-DEPENDENT DIABETES MELLITUS | UPJOHN CO (US) | 2001-09-05 | — | — | EP | claimed |
| EP-0793646-B1 | AMINOGUANIDINE CARBOXYLATES FOR THE TREATMENT OF NON-INSULIN-DEPENDENT DIABETES MELLITUS | UPJOHN CO (US) | 2001-09-05 | — | — | EP | disclosed |