Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 17/20 | 0.55 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3756255 | 0.86 | PRKDC (0.64) | PRKDCPIK3CARIPK1CREBBP | |
| SCHEMBL3715225 | 0.86 | PRKDC (0.70) | PRKDCPIK3CARIPK1 | |
| SCHEMBL3756766 | 0.86 | PRKDC (0.63) | PRKDCPIK3CARIPK1CREBBP | |
| SCHEMBL3760305 | 0.86 | PRKDC (0.63) | PRKDCPIK3CARIPK1 | |
| SCHEMBL3755287 | 0.86 | PRKDC (0.63) | PRKDCPIK3CARIPK1CREBBP | |
| SCHEMBL7862288 | 0.85 | PRKDC (0.55) | PRKDCPIK3CARIPK1CREBBP | |
| SCHEMBL3754519 | 0.85 | PRKDC (0.62) | PRKDCPIK3CARIPK1 | |
| SCHEMBL3753883 | 0.85 | PRKDC (0.81) | PRKDCPIK3CARIPK1 | |
| SCHEMBL3752371 | 0.85 | PRKDC (0.67) | PRKDCPIK3CARIPK1 | |
| SCHEMBL3761401 | 0.85 | PRKDC (0.62) | PRKDCPIK3CARIPK1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118208-A1 | BENZOXAZEPIN-4- (5H) -YL DERIVATIVES AND THEIR USE TO TREAT CANCER | EXELIXIS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |