Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 8/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859886 | 0.90 | NR1H2 (0.46) | ABCB1NR1H2NR1H3MEN1KMT2A | |
| SCHEMBL7862618 | 0.86 | GPR119 (0.42) | ABCB1NR1H2NR1H3GPR119 | |
| SCHEMBL8046698 | 0.85 | NR1H2 (0.38) | ABCB1NR1H2NR1H3GPR119MEN1 | |
| SCHEMBL8047012 | 0.85 | NR1H2 (0.38) | ABCB1NR1H2NR1H3GPR119MEN1 | |
| SCHEMBL7860716 | 0.83 | ABCB1 (0.40) | ABCB1NR1H2NR1H3GPR119 | |
| SCHEMBL139880 | 0.83 | NR1H2 (0.42) | ABCB1NR1H2MEN1KMT2ASRC | |
| SCHEMBL21286125 | 0.83 | NR1H2 (0.42) | ABCB1NR1H2MEN1KMT2ASRC | |
| SCHEMBL1372634 | 0.83 | NR1H2 (0.42) | ABCB1NR1H2MEN1KMT2ASRC | |
| SCHEMBL20312947 | 0.83 | NR1H2 (0.42) | ABCB1NR1H2MEN1KMT2ASRC | |
| SCHEMBL19964151 | 0.83 | NR1H2 (0.42) | ABCB1NR1H2MEN1KMT2ASRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747381-B1 | CARBAPENEM DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5707987-A | BACTERICIDE ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0747381-A1 | CARBAPENEM DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |